Best Fertility Supplements for Egg Quality (2026)
Egg quality is one of the most critical factors in female fertility, and it naturally declines with age as mitochondrial function in oocytes decreases. Supplements like CoQ10, DHEA, myo-inositol, and key antioxidants have shown promise in clinical research for supporting egg health, ovarian response, and conception outcomes. Here are the best fertility supplements specifically formulated for egg quality.
Quick Comparison
| Product | Key Ingredient | Form | Best For | Rating |
|---|---|---|---|---|
| Pink Stork Fertility Supplements | Inositol + CoQ10 | Capsules | Best Overall | 4.4/5 |
| Pink Stork Premium Fertility Gummies | CoQ10 + Myo-Inositol + Probiotics | Gummies | Best Gummies | 4.3/5 |
| Pink Stork Fertility 2-in-1 | Inositol + Folate + CoQ10 | Capsules | Best Comprehensive | 4.4/5 |
| Needed Egg Quality Support | CoQ10 + Alpha-Lipoic Acid + NAC | Capsules | Best Antioxidant Formula | 4.7/5 |
| Theralogix NeoQ10 | CoQ10 (Ubiquinol) 100mg | Softgels | Best CoQ10 for Fertility | 4.6/5 |
| Molecular Fertility CoQ10 Ubiquinol | Ubiquinol with VESIsorb | Softgels | Best Absorption | 4.5/5 |
| Ovasitol by Theralogix | Myo-Inositol + D-Chiro-Inositol | Powder | Best for PCOS | 4.7/5 |
1. Pink Stork Fertility Supplements — Best Overall
- Natural Fertility Support for Women (TTC): Pink Stork Fertility Support is thoughtfully formulated to help nourish your body’s natural fertility process and is more comprehensive than standalone inositol products, blending essential nutrients and supportive herbal ingredients in one 2-in-1 daily female fertility supplement + prenatal vitamin, so no need for a separate prenatal multivitamin. Designed to support hormone balance, reproductive wellness, ovarian health, and cycle regularity - because your journey to conception deserves gentle, consistent care from within. From a women-led brand that prioritizes clarity over hype. Take 2 capsules a day with or without food, 30 servings.
- Science-Backed Nutrients: Our formula includes Myo-Inositol powder and L-5-MTHF (methylated folate) - the active, bioavailable form of folate your body can use, unlike synthetic folic acid that must be converted first - two clinically studied nutrients that play key roles in supporting healthy ovulation, ovarian function, and reproductive health. Thoughtfully included to align with how many TTC shoppers build their plans, with simple directions for consistent use - helping empower you to feel informed and confident as you care for your fertility routine.
- Herbal Support for Cycle Regularity + Hormone Harmony: Features Vitex (Chasteberry), Organic Ashwagandha, Shatavari, and complementary botanicals often chosen during preconception to support healthy hormone balance and a predictable cycle. Our products are realistic - no guarantees, no timelines - just supportive ingredients you can understand and use daily. Clear label, straightforward routine, and easy to take wherever life takes you- at home or on the go - with room to personalize with your provider’s guidance.
- Nutrient-Rich Formula for Preconception Wellness: With CoQ10, iron, zinc, and B vitamins, this formula provides comprehensive nutritional support for reproductive health, along with vitamins important for preconception nutrition. These ingredients help nourish egg quality, support cellular energy, and contribute to hormone regulation - key elements for women TTC. As with any products designed to support hormonal health, Fertility Support may impact your cycle. For best results, we recommend consistent use for at least 3 months; discontinue use once you receive a positive pregnancy test and transition to a prenatal vitamin. Pair with Pink Stork's Fertility Tea and Wild Yam Cream.
- Women-Owned: Pink Stork is women-owned and women-run, founded by a Certified Health Coach committed to clear language and thoughtful formulas. Every bottle is produced with rigorous quality standards and transparent labeling that you can read at a glance. Add it to your TTC routine to support ovulation, cycle balance, and everyday reproductive wellness. Our goal: make the “what should I take?” question feel manageable, with a formula you can stick with over time. Our Fertility Support capsules are vegan, non-GMO, and made without gluten, soy, or artificial ingredients. Third-party tested for purity, UV-protected bottle, crafted with care, & guided by science.
Pink Stork’s Fertility capsules combine myo-inositol and CoQ10 with essential vitamins to support ovulation, hormone balance, and egg quality in one convenient formula.
Each serving delivers a targeted blend of myo-inositol, CoQ10, folate, vitamin B6, and vitamin D — all key nutrients studied for their roles in female reproductive health. The formula is specifically designed for women trying to conceive, supporting healthy ovulation cycles and cellular energy production in eggs. Each bottle contains 60 capsules (30-day supply). Manufactured in a GMP-certified facility and third-party tested.
- Pros:
- Combines inositol and CoQ10 — two of the most researched egg quality nutrients
- Includes folate and vitamin D for comprehensive preconception support
- Well-known fertility brand trusted by OB-GYNs
- Cons:
- CoQ10 dose is lower than standalone CoQ10 supplements
- May need to pair with additional supplements for higher CoQ10 dosing
Best for: Women looking for an all-in-one fertility supplement that addresses egg quality, ovulation, and preconception nutrition
2. Pink Stork Premium Fertility Gummies — Best Gummies
- Hormone Balance for Women: Trying to conceive shouldn’t feel like guesswork. Pink Stork Premium Fertility Gummies deliver daily support for your body’s natural reproductive rhythm — with 13 key ingredients recommended by OBGYNs and specialists.
- Expert-Backed Conception for Women: Support your menstrual cycle, ovarian health, hormonal health, egg quality, and luteal phase with two tasty gummies daily. Formulated with Myo-Inositol, CoQ10, and Methylated Folate (the natural, more bioavailable form of folic acid) to help support hormone balance, reproductive health, normal ovulation, cycle regularity, and energy, while CoQ10 and B-Vitamins fuel your cells for the energy your body needs on this journey. Delicious, nutrient-packed, and crafted to support your chances of conception. For best results, take for at least 3 months prior to conception.
- Hormone Harmony + Reproductive Wellness: Balanced hormones are the foundation of fertility. Our blend of vitamins and minerals supports natural hormone balance, ovulation rhythm, and healthy reproductive function. With Vitamin D, Zinc, Selenium, and B12, this clean formula nourishes your body from the inside out, so you can feel more in control of your fertility journey. No more chalky pills or complicated routines. These delicious, mango pineapple-flavored bite-sized gummies make it easy to enjoy fertility-focused nutrients in a convenient daily ritual—perfect for wherever life takes you.
- Clean, Vegan, and Delicious: No mystery ingredients or artificial extras here — just delicious mango pineapple gummies and clean, vegan-friendly nutrition. Third-party tested in GMP-certified facilities, our gummies meet the highest manufacturing standards. Free from GMOs, gluten, soy, and artificial colors and flavors, so you can enjoy them with confidence. Enjoy as part of your ritual with additional Pink Stork Fertility products - including our Fertility Tea (with Vitex and Red Raspberry Leaf) or Myo-Inositol & D-Chiro Inositol supplements. And don't forget Blue Stork Fertility Supplements for men! Once a positive pregnancy test occurs, change to a prenatal like Total Prenatal + DHA.
- Created by Women, For Women: We know the TTC journey isn’t always easy — but we are here to take the guesswork out of your nutrition. Formulated by women’s health experts, crafted with care, made in the USA, and third-party tested for purity, Pink Stork delivers support you can trust. Women-owned, women-run, and backed by experts— we’re here to walk with you every step of the way. As always, we recommend consulting your healthcare provider before using this product alongside medications or other supplements to ensure your personal needs are met. No refrigeration needed.
For women who struggle with capsules, Pink Stork’s fertility gummies deliver CoQ10, myo-inositol, and probiotics in a delicious chewable format.
These gummies combine CoQ10, myo-inositol, and a probiotic blend to support egg quality, hormonal balance, and reproductive health. The addition of probiotics supports gut health, which plays a role in hormone metabolism and nutrient absorption. Naturally flavored and colored, with no artificial sweeteners. Each bottle provides a 30-day supply.
- Pros:
- Gummy format makes daily supplementation easy and enjoyable
- Includes probiotics for gut-hormone connection support
- No artificial flavors, colors, or sweeteners
- Cons:
- Lower potency per serving compared to capsule formulations
- Contains added sugars inherent to gummy form
Best for: Women who prefer a tasty gummy supplement for daily fertility support
3. Pink Stork Fertility 2-in-1 — Best Comprehensive
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This 2-in-1 formula combines fertility-specific ingredients with prenatal nutrition, streamlining the supplement routine for women actively trying to conceive.
The formula pairs myo-inositol and CoQ10 for egg quality support with methylated folate, iron, and other prenatal essentials. This eliminates the need to take separate fertility and prenatal supplements. Designed for the preconception through early pregnancy window when both egg quality and foundational nutrition matter most. Doctor-formulated and manufactured in the USA.
- Pros:
- Combines fertility and prenatal support in one product
- Uses methylated folate for better bioavailability
- Simplifies the supplement routine during TTC
- Cons:
- Individual ingredient doses may be lower than dedicated standalone supplements
- Not suitable for women needing high-dose CoQ10 (400–600 mg)
Best for: Women who want to combine fertility and prenatal supplementation into a single product
4. Needed Egg Quality Support — Best Antioxidant Formula
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Needed’s Egg Quality Support is one of the few supplements specifically formulated by fertility nutritionists to combat oxidative stress in egg cells with a targeted antioxidant stack.
This formula includes CoQ10, alpha-lipoic acid (ALA), N-acetylcysteine (NAC), and vitamin E — a combination designed to protect eggs from free radical damage and support mitochondrial function. Each ingredient is included at clinically relevant doses based on reproductive health research. Third-party tested by NSF, non-GMO, and free from major allergens. Available in a 30-day supply.
- Pros:
- Targeted antioxidant formula specifically designed for egg quality
- Includes ALA and NAC — antioxidants recommended by fertility specialists
- NSF-certified for purity and potency
- Cons:
- Premium price point
- Does not include inositol, so may need to be paired with additional supplements
Best for: Women over 35 or those with diminished ovarian reserve seeking targeted antioxidant protection for egg cells
5. Theralogix NeoQ10 — Best CoQ10 for Fertility
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NeoQ10 is an NSF-certified CoQ10 supplement specifically marketed for fertility, delivering 100 mg of enhanced-absorption CoQ10 in a softgel designed for reproductive health.
Each softgel provides 100 mg of CoQ10 in a lipid-based delivery system for improved absorption. Theralogix is one of the most recommended brands by reproductive endocrinologists and fertility clinics nationwide. The formula is NSF Certified for Sport, meaning it undergoes rigorous third-party testing for purity and label accuracy. A 90-softgel bottle provides a 90-day supply at one per day, or 30 days at three per day for higher dosing protocols.
- Pros:
- NSF certified — one of the most stringent third-party certifications available
- Recommended by reproductive endocrinologists and fertility clinics
- Enhanced absorption formula for better bioavailability
- Cons:
- Higher cost per serving than generic CoQ10 supplements
- 100 mg per softgel — may need multiple daily for 300–600 mg fertility protocols
Best for: Women following a fertility specialist’s CoQ10 protocol who want a clinically trusted, NSF-certified option
6. Molecular Fertility CoQ10 Ubiquinol — Best Absorption
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This fertility-specific ubiquinol supplement uses patented VESIsorb technology and Kaneka QH to deliver the active form of CoQ10 with dramatically enhanced absorption.
Unlike standard CoQ10 (ubiquinone), this supplement uses ubiquinol — the reduced, active form that’s more readily utilized by the body. The VESIsorb delivery system has been shown in studies to increase CoQ10 absorption by up to 3x compared to standard formulations. Each softgel contains 100 mg of Kaneka QH ubiquinol. Developed in collaboration with reproductive health researchers. GMP and NSF certified.
- Pros:
- Active ubiquinol form — more bioavailable than standard ubiquinone
- VESIsorb technology for significantly enhanced absorption
- Developed specifically for female reproductive health
- Cons:
- Premium pricing reflects advanced delivery technology
- Smaller softgel count per bottle than some competitors
Best for: Women who want the most bioavailable form of CoQ10 specifically designed for egg health support
7. Ovasitol by Theralogix — Best for PCOS
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Ovasitol is the leading myo-inositol and D-chiro-inositol supplement for PCOS, delivering the researched 40:1 ratio shown to improve ovulation, insulin sensitivity, and egg quality.
Each serving provides 2,000 mg of myo-inositol and 50 mg of D-chiro-inositol in the clinically studied 40:1 ratio. This specific ratio has been shown in multiple studies to support regular ovulation, improve insulin sensitivity, and enhance egg quality in women with PCOS. The unflavored powder dissolves easily in water. NSF certified and recommended by over 45,000 healthcare practitioners. A 90-day supply comes in convenient individual packets or a canister.
- Pros:
- Clinically studied 40:1 myo-inositol to D-chiro-inositol ratio
- NSF certified with strong clinical evidence for PCOS
- Recommended by tens of thousands of healthcare providers
- Cons:
- Specifically targeted for PCOS — less relevant for non-PCOS egg quality concerns
- Does not include CoQ10, folate, or other fertility vitamins
Best for: Women with PCOS seeking to improve ovulation, insulin sensitivity, and egg quality with the most researched inositol ratio
8. Life Extension DHEA 25mg — Best DHEA Supplement
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Life Extension’s DHEA provides pharmaceutical-grade 25 mg micronized DHEA, the dosage most commonly recommended by fertility specialists for women with diminished ovarian reserve.
DHEA (dehydroepiandrosterone) is a hormone precursor that supports the ovarian environment for egg development. Research suggests DHEA supplementation may improve egg quality, ovarian response, and IVF outcomes in women with diminished ovarian reserve. Life Extension uses micronized DHEA for improved absorption. Each bottle contains 100 vegetarian capsules. Non-GMO and manufactured under strict GMP standards.
- Pros:
- 25 mg dose matches the most common fertility protocol (25 mg 2–3x daily)
- Micronized for enhanced absorption
- Affordable price from a trusted supplement brand
- Cons:
- DHEA should only be taken under medical supervision
- May cause side effects like acne, oily skin, and hair growth
Best for: Women with diminished ovarian reserve who have been advised by their fertility doctor to supplement with DHEA
How to Choose the Best Fertility Supplement for Egg Quality
The most evidence-backed nutrients for egg quality include CoQ10 (supports mitochondrial energy in egg cells), myo-inositol (improves ovulation and insulin signaling, especially for PCOS), DHEA (supports the ovarian environment for egg maturation), and antioxidants like alpha-lipoic acid, NAC, and vitamin E that protect eggs from oxidative damage. For women over 35 or those with diminished ovarian reserve, a combination approach targeting multiple pathways is often recommended by fertility specialists.
CoQ10 dosages in fertility research typically range from 200–600 mg daily, with many reproductive endocrinologists recommending 400–600 mg. Ubiquinol (the active form) is more bioavailable than ubiquinone and may be effective at lower doses. Myo-inositol is typically dosed at 2,000–4,000 mg daily. DHEA is commonly prescribed at 25 mg two to three times daily, but should only be used under medical supervision.
Capsules and softgels generally deliver higher potencies of egg quality nutrients than gummies. For CoQ10 specifically, softgels with lipid-based delivery systems improve absorption significantly since CoQ10 is fat-soluble. Powdered inositol can be mixed into beverages for easier consumption at higher doses.
Look for supplements that are third-party tested (NSF or USP certification provides the highest assurance), GMP-certified, and transparent about ingredient sources. For CoQ10, Kaneka is the most trusted raw material supplier. Always consult with a reproductive endocrinologist before starting a fertility supplement regimen, especially for DHEA.
Frequently Asked Questions
What supplements improve egg quality?
The most researched supplements for egg quality include CoQ10 (supports mitochondrial function in eggs), myo-inositol (improves ovulation and egg maturation, especially in PCOS), DHEA (supports the hormonal environment for egg development), and antioxidants like alpha-lipoic acid, NAC, and vitamin E that protect eggs from oxidative stress. Folate and vitamin D are also foundational for reproductive health.
How much CoQ10 should I take for egg quality?
Most fertility specialists recommend 200–600 mg of CoQ10 daily for egg quality support. Some protocols use 200 mg three times daily (600 mg total). Ubiquinol, the active form, may be effective at lower doses due to better bioavailability. Start at least 2–3 months before trying to conceive, as egg maturation takes approximately 90 days.
When should I start taking fertility supplements?
Ideally, begin fertility supplements at least 90 days (3 months) before trying to conceive. This aligns with the egg maturation cycle — it takes approximately 90 days for an egg to develop from a primordial follicle to an ovulation-ready oocyte. Starting early gives supplements time to influence egg quality during this critical window.
Are fertility supplements safe to take with IVF medications?
Many fertility supplements, including CoQ10 and inositol, are commonly used alongside IVF protocols. However, DHEA and certain herbal ingredients may interact with fertility medications or hormonal treatments. Always discuss your full supplement regimen with your reproductive endocrinologist before starting or continuing supplements during an IVF cycle.
Can inositol help with egg quality if I don’t have PCOS?
While myo-inositol has the strongest evidence for women with PCOS, emerging research suggests it may also support egg quality and oocyte maturation in non-PCOS populations. Inositol plays a role in intracellular calcium signaling during fertilization and early embryo development, making it potentially beneficial for a broader range of fertility concerns.
How long do fertility supplements take to work?
Most fertility supplements require 2–3 months of consistent use to meaningfully impact egg quality, since the egg maturation cycle is approximately 90 days. CoQ10 and antioxidants need time to accumulate and influence mitochondrial function at the cellular level. DHEA typically shows effects on ovarian response within 2–4 months of supplementation.
