Best Liposomal Magnesium Supplements (2026)
Liposomal magnesium supplements use lipid-based delivery technology to encapsulate magnesium in tiny phospholipid spheres, protecting it from degradation in the digestive tract and significantly improving absorption. This advanced delivery method makes liposomal magnesium an excellent option for people who experience GI discomfort with standard magnesium or who want maximum bioavailability from each dose.
Quick Comparison
| Product | Key Ingredient | Form | Best For | Rating |
|---|---|---|---|---|
| Selerb 18-in-1 Liposomal Magnesium Complex | 18 Types Magnesium 1400mg | Capsules | Best Overall | 9.5/10 |
| Codeage Liposomal Magnesium Glycinate | Mag Bisglycinate 350mg + BioPerine | Capsules | Best Premium | 9.4/10 |
| MaryRuth Organics Magnesium Liposomal | Mag Bisglycinate 135mg | Liquid | Best Liquid | 9.3/10 |
| Oakevlp 29-in-1 Liposomal Magnesium Complex | 18 Active Mag Types 1400mg | Capsules | Best Value | 9.2/10 |
| Cymbiotika Liposomal Magnesium Complex | Mag Taurate + Bisglycinate + GIVOMAG | Liquid Pouches | Best for Sleep | 9.2/10 |
| Manna Liposomal Magnesium | Mag Bisglycinate 135mg | Liquid | Best for Brain Health | 9.0/10 |
| Gulapelst 2-Pack Liposomal Magnesium Complex | 12 Mag Types 1400mg | Capsules | Best Budget Pick | 8.9/10 |
1. Selerb 18-in-1 Liposomal Magnesium Complex – Best Overall
- Full Spectrum 18-in-1 Magnesium Complex: Selerb Magnesium Complex delivers 300 mg of elemental magnesium from 12 complementary forms, including magnesium chloride, glycinate, ascorbate, carbonate, aspartate, gluconate, oxide, malate, citrate, lactate, taurate, and orotate. This full-spectrum magnesium complex is designed for balanced daily mineral support and overall wellness.
- Magnesium Complex For Women & Men: This advanced magnesium complex for women and men supports daily calm, muscle comfort, and overall balance. Suitable for both magnesium complex for women seeking relaxation and hormonal balance, and magnesium complex for men supporting recovery and mineral replenishment.
- Liposomal High-Absorption System: Formulated with a liposomal delivery system, this magnesio complex combines magnesium with targeted cofactors Vitamin B6, D3, K2, and Zinc to support efficient absorption and utilization—helping your body make the most of every serving.
- Stomach-Friendly Digestive Comfort Support: Enhanced with DGL Licorice Root and Slippery Elm Bark, this gentle magnesium supplement is designed to support digestive comfort and daily tolerance, making it suitable for sensitive systems seeking full-spectrum magnesium support.
- Magnesium For Sleep, Calm & Daily Balance: Selerb provides daily magnesium for sleep and relaxation, supporting nighttime calm, muscle relaxation, nerve balance, and long-term bone health through balanced mineral and calcium support. Vegan-friendly, gluten-free, and made in a cGMP-certified U.S. facility, with third-party testing for purity and potency.
Selerb delivers a comprehensive liposomal magnesium complex with 18 active forms of magnesium in a single capsule, making it one of the most well-rounded options on the market.
Each serving provides 1400mg of magnesium from multiple forms including glycinate, citrate, malate, taurate, and L-threonate. The formula is enhanced with vitamin D3, K2, B6, zinc, DGL licorice root, and slippery elm bark to support both absorption and digestive comfort. Manufactured in a cGMP-certified U.S. facility with third-party testing for purity and potency.
- Pros:
- 18 different magnesium forms for comprehensive coverage
- Includes cofactors (D3, K2, B6, zinc) that enhance utilization
- Stomach-friendly formula with DGL licorice root and slippery elm
- Cons:
- Higher price point than single-form magnesium
- May be more complex than some users need
Best for: Anyone seeking a comprehensive, high-absorption magnesium supplement with multiple forms and digestive support
2. Codeage Liposomal Magnesium Glycinate – Best Premium
- High-Quality Magnesium Bisglycinate: Codeage Liposomal Magnesium Glycinate capsule supplement provides 350 mg of magnesium bisglycinate and magnesium oxide per serving.
- Liposomal Delivery: This magnesium glycinate capsule supplement features a modern liposomal delivery made with a phospholipid complex utilizing non-GMO sunflower oil for added purity.
- Enhanced with BioPerine: This magnesium supplement is enriched with BioPerine, a black pepper extract standardized to 95% piperine.
- 2-Month Supply: Codeage Liposomal Magnesium Glycinate Supplement capsule is vegan, non-GMO, gluten-free, dairy-free, and soy-free. Each bottle comes with 60 servings for 2 months of supply.
- Manufactured in the USA: This chelated magnesium glycinate formula is manufactured in the USA with global ingredients in a cGMP-certified facility for quality and purity.
Codeage combines liposomal delivery with chelated magnesium bisglycinate and BioPerine black pepper extract for a premium absorption-focused formula.
Each serving delivers 350mg of magnesium from bisglycinate chelate, wrapped in a phospholipid complex made from non-GMO sunflower oil and lecithin. The addition of BioPerine (standardized to 95% piperine) further enhances bioavailability. The 240-count bottle provides a 2-month supply at 4 capsules per day. Vegan, non-GMO, gluten-free, dairy-free, and soy-free. Manufactured in the USA in a cGMP-certified facility.
- Pros:
- Chelated bisglycinate form for gentle, high absorption
- BioPerine enhances nutrient uptake
- 2-month supply per bottle is excellent value
- Cons:
- 4 capsules per serving may be inconvenient for some
- Contains magnesium oxide as a secondary source
Best for: Those who want a premium liposomal magnesium glycinate with enhanced absorption from BioPerine
3. MaryRuth Organics Magnesium Liposomal – Best Liquid
- Magnesium Liposomal: Support your Magnesium status with this almond-vanilla flavored Magnesium Calm Liposomal! Magnesium, an essential mineral, is vital for many processes in the body and it’s estimated that almost half of U.S. adults do not intake the recommended amount of Magnesium.
- Multiple Benefits: Magnesium is vital for many processes in the body such as muscle and nerve function, bone health, and calcium absorption. Magnesium may also support mood. The optimal amount of Magnesium is also important for normal sleep regulation.
- Enhanced Absorption: Liposomes are tiny spherical structures that have a protective outer layer and an inner cavity to hold and transport substances such as vitamins or other nutrients to the body. Our products’ liposomal delivery system works by encapsulating the vitamins/nutrients into liposomal structures, allowing these nutrients to be easily absorbed in the gut.
- Easy-to-Take-Liposomal: Take 1 Tablespoon (15 mL) daily. Can be taken directly or added to your choice of blended beverage or as a topping on a variety of foods. Store in a cool, dry place. Refrigerate after opening. Each bottle comes with 30 servings.
- For Most Lifestyles: MaryRuth's Magnesium Calm Liposomal is Non-GMO, Vegan, Dairy Free, Gluten & Wheat Free, Soy Free, Sugar Free. No Artificial Colors, Made in a GMP Facility. B Corp Certified. This product CONTAINS nut allergens: Coconut-derived glycerin and almond butter.
MaryRuth’s liquid liposomal formula offers a convenient, great-tasting alternative to capsules with their almond-vanilla flavored magnesium bisglycinate.
Each tablespoon provides 135mg of magnesium as bisglycinate, encapsulated in a liposomal proprietary blend with organic sunflower seed oil and phosphatidylcholine. The liquid format allows for easy dosage adjustment and can be taken directly or mixed into beverages. The bottle provides 30 servings. Non-GMO, vegan, dairy-free, gluten and wheat-free, soy-free, and sugar-free. B Corp certified and made in a GMP facility. For those interested in other forms, check out our guide to liquid magnesium supplements.
- Pros:
- Liquid format is easy to take and adjust dosing
- Pleasant almond-vanilla flavor
- B Corp certified with clean ingredient list
- Cons:
- Lower magnesium content per serving (135mg) compared to capsule options
- Must refrigerate after opening
Best for: Adults who prefer liquid supplements or have difficulty swallowing capsules
4. Oakevlp 29-in-1 Liposomal Magnesium Complex – Best Value
- 【Mild & Highly Efficient Magnesium Complex】: 29-in-1 Magnesium supplement with 18 active magnesium types 1000mg per serving with magnesium L-threonate, magnesium glycinate, magnesium malate, magnesium citrate, pidolate, lactate, chloride, aspartate, orotate, taurate, succinate, gluconate, carbonate, acetate etc.Combined with complete B complex, vitamin D3 K2, unlock the benefits of magnesio from supporting normal energy metabolism, bone, muscle function and mental performance to overall wellness.
- 【Stable & Reliable Sleep】: Oakevlp chelated magnesium as a high-quality supplement, magnesium l-threonate, glycinate, taurate, malate and pidolate work together to support relaxation and maintain normal nervous system function. These gentle, highly absorbable forms help ease occasional muscle tension, calm restlessness.By supporting balanced nerve signaling, neurotransmitter production and muscle relaxation, they create optimal conditions for falling asleep and enjoying deep, restorative rest.
- 【He❤rt Bone & More Functions Support】: Magnesium Citrate, Chloride, Orotate, Oxide, Gluconate and Acetate work together to help maintain normal he❤rt rhythm, support cardiovascular function and promote proper electrolyte balance. This powerful synergy of high-potency Magnesium, Complete B-Complex, Vitamin D3 K2 Synergy enhances bone density, maintains normal muscle function and supports a robust immune system. By support musculoskeletal during daily activity, they help maintain overall wellness.
- 【Highly Absorbent & Friendly To Stomach Intestines】: Oakevlp liposomal magnesium complex capsules unlike traditional magnesium supplements, our formula encapsulates magnesium in liposomes, protecting it from degradation and improving cellular uptake. Unique liposomal delivery system enhances bioavailability and it is friendly to the stomach and intestines, making it suitable for people who need magnesium supplementation ensuring that your body efficiently absorbs this essential mineral.
- 【Quality Satisfaction】: Each of Oakevlp liposomal magnesium complex capsules supplement is produced in GMP-certified facilities with the strictest quality control standards. All batches have quality assurance at every stage of production.If you have any questions, please contact us via email and we will provide you with a 100% ideal solution.
Oakevlp packs 18 active magnesium types plus supporting vitamins and minerals into a liposomal capsule at a competitive price point.
Each serving delivers 1000mg of magnesium from diverse forms including L-threonate, glycinate, malate, citrate, taurate, and more. Enhanced with a complete B-complex, vitamin D3, K2, and CoQ10. The liposomal delivery system protects magnesium from degradation and improves cellular uptake while remaining gentle on the stomach. Produced in GMP-certified facilities with quality assurance at every production stage.
- Pros:
- Excellent price-to-value ratio with 29 ingredients
- Includes CoQ10 and B-complex vitamins
- Stomach-friendly liposomal delivery
- Cons:
- Newer brand with less market history
- Complex formula may include more than needed for simple magnesium supplementation
Best for: Budget-conscious buyers who want a comprehensive magnesium complex without the premium price
5. Cymbiotika Liposomal Magnesium Complex – Best for Sleep
- 3-IN-1 HIGH ABSORPTION FORMULA: Cymbiotika’s Liposomal Magnesium Complex combines three bioavailable forms — Magnesium Taurate, Magnesium Bisglycinate, and Magnesium Glycerophosphate — for maximum absorption and gentle digestion.*
- SUPPORTS HEART & CARDIOVASCULAR HEALTH: Magnesium helps regulate calcium balance, promotes healthy lipid metabolism, and supports antioxidant activity for optimal vascular function.
- PROMOTES RELAXATION & RESTFUL SLEEP: Formulated to help the body respond to occasional stress, support mood balance, and promote calmness and quality sleep.*
- WHOLE-BODY WELLNESS SUPPORT: Essential for over 300 enzymatic processes, this formula helps maintain healthy energy production, muscle function, and nervous system balance.*
- NATURAL SUPPLEMENT: Cymbiotika strives to create ingredients you can trust. We combine scientific innovation with traditional Eastern medicine to design formulas that synergize with the body. Our magnesium supplement utilizes the most advanced absorption technology and is vegan, keto, GMO-free, and made with ZERO chemicals, animal products, alcohols, additives, and preservatives.
Cymbiotika uses advanced liposomal technology to deliver three highly absorbable magnesium forms in convenient single-serve liquid pouches.
Each pouch combines magnesium taurate, magnesium bisglycinate, and GIVOMAG magnesium glycerophosphate — a clinically proven form with the lowest incidence of GI distress. The formula also includes phosphatidylcholine from sunflower lecithin. Vanilla almond flavored, vegan, keto-friendly, GMO-free, and made with zero chemicals, additives, or preservatives. Each box contains 28 pouches. If sleep is your primary goal, you may also want to explore our guide to magnesium for sleep supplements.
- Pros:
- GIVOMAG is clinically proven for minimal GI distress
- Single-serve pouches are convenient for travel
- Three synergistic magnesium forms
- Cons:
- Premium price point (one of the more expensive options)
- Contains coconut and almond allergens
Best for: Those prioritizing sleep support and relaxation with a premium, gentle-on-the-gut formula
6. Manna Liposomal Magnesium – Best for Brain Health
- Promotes Relaxation & Proper Sleep: Manna's magnesium supplement works to soothe your mind and muscles, curbing restlessness. It aids in maintaining GABA levels that signal sleep time, ensuring drowsiness once you lay down. Boost your relaxation with magnesium glycinate liquid and enjoy quality sleep.
- Supports Healthy Brain Function: Liquid magnesium glycinate, a key brain receptor moderator, helps with brain growth, memory, and learning. Beyond enhancing daily cognitive abilities like concentration and memory, this essential mineral supports a gracefully aging brain with 135mg of highly bioavailable magnesium.
- Encourages Good Mood & Mental Clarity: The powerful mood-boosting abilities of magnesium bisglycinate aim to regulate stress. This magnesium supplement for women and men keeps you at your best despite life's challenges. Foster a positive mindset and sharp mental performance and clarity.
- Fortifies Bones & Muscle: This liquid magnesium supplement aids in cellular growth and bone repair, preserving density for robust, healthy bones. Low magnesium can lead to muscle over-contraction, cramps, or spasms. It ensures smooth muscle function by facilitating relaxation after they contract.
- Nutrients Absorb 10x Better than Traditional Supplements: Using NANOFUSE technology, our magnesium supplements are formulated with liposomes which act as life jackets for nutrients. This results in 10x the absorption compared to traditional supplements, so the benefits you get are always elevated!
Manna’s NANOFUSE liposomal technology claims up to 10x better absorption than traditional supplements, making it a standout for cognitive support.
Each serving delivers 135mg of highly bioavailable magnesium bisglycinate in liquid form. The NANOFUSE liposomal delivery system encapsulates magnesium in lipid structures that act as protective carriers through the digestive tract. The formula focuses on supporting brain function, GABA levels, memory, and learning alongside muscle relaxation and sleep. Small-batch produced by a U.S.-based company focused on absorption science.
- Pros:
- Proprietary NANOFUSE absorption technology
- Specifically designed for cognitive and mood support
- Clean ingredient list from a small-batch producer
- Cons:
- Lower magnesium per serving compared to capsule alternatives
- Smaller brand with less widespread availability
Best for: Adults focused on brain health, mood support, and cognitive performance
7. Gulapelst 2-Pack Liposomal Magnesium Complex – Best Budget Pick
- 【Comprehensive Magnesium Complex】: Gulapelst Liposomal Magnesium complex capsules formula features a powerful blend of 12 distinct magnesium forms, including Magnesium Glycinate, Citrate and Malate ect, delivering 1000mg of magnesium per serving for optimal absorption and efficacy. These various magnesium compounds offer a range of benefits, making them essential for maintaining optimal physical and mental well-being.
- 【Liposomal Absorption】: Utilizing advanced liposomal technology, these capsules encapsulate active nutrients in microscopic lipid bubbles, ensuring a remarkable 98 times greater absorption compared to non-liposomal magnesium forms, allowing your body to fully utilize its powerful ingredients. With a unique combination of 12 magnesium chelates, maximizing the full health benefits that magnesium has to offer.
- 【Promotes Optimal Muscle Function and Energy Production】: Gulapelst Magnesium Complex Capsules are designed to support optimal muscle function and enhance your body's energy production. Magnesium plays a crucial role in muscle contraction and relaxation, helping to reduce cramps and soreness after workouts. This makes our capsules a vital addition to your daily routine, whether you're an athlete or simply looking to maintain an active lifestyle, ensuring you stay energized throughout the day.
- 【Enhances Sleep Quality and Promotes Relaxation】: Struggling with sleep? Gulapelst unique magnesium formulation helps you achieve longer and deeper sleep cycles. By promoting relaxation and reducing stress, these capsules create the ideal environment for restorative sleep, making it easier to fall asleep and stay asleep. Suitable for men and women of all ages, our Magnesium Complex is your go-to solution for enhanced sleep quality and overall relaxation.
- 【Quality Satisfaction】: Each of Gulapelst liposomal magnesium complex capsules supplement is produced in GMP-certified facilities with the strictest quality control standards. All batches have quality assurance at every stage of production. If you have any questions, please contact us via email and we will provide you with a 100% ideal solution.
This 2-pack delivers 12 active magnesium forms with D3, B6, B12, ashwagandha, and CoQ10 at one of the lowest per-serving prices in the liposomal category.
Each serving provides 1000mg of magnesium from glycinate, citrate, malate, and nine additional forms. The two-bottle bundle delivers 240 total capsules for an extended supply. Enhanced with ashwagandha for stress support and CoQ10 for cellular energy. The liposomal capsule format protects ingredients through digestion. Produced in GMP-certified facilities. For those also dealing with anxiety, our guide to magnesium for anxiety covers additional options.
- Pros:
- Two-bottle bundle offers outstanding value
- Includes ashwagandha and CoQ10 as added bonuses
- 12 magnesium forms for broad mineral coverage
- Cons:
- Less established brand
- Some may prefer a simpler formula without adaptogens
Best for: Value-focused shoppers who want a multi-form liposomal magnesium with stress and energy support
How to Choose the Best Liposomal Magnesium Supplement
Liposomal delivery is one of the most effective ways to improve magnesium absorption, but not all liposomal products are created equal. Look for supplements that use phosphatidylcholine or sunflower lecithin as the lipid carrier, as these create the most stable liposomal structures. Products that simply list “liposomal” without specifying the phospholipid source may not deliver true liposomal benefits.
The form of magnesium inside the liposome matters just as much as the delivery system. Magnesium bisglycinate (glycinate) is among the most bioavailable and gentlest on the stomach. Magnesium L-threonate is the only form clinically shown to cross the blood-brain barrier, making it ideal for cognitive support. Multi-form complexes offer broader coverage but may dilute the amount of any single form.
Dosage ranges for magnesium supplementation typically fall between 200-400mg of elemental magnesium daily for adults, though individual needs vary. Check whether the label lists total magnesium compound weight or actual elemental magnesium — these can differ significantly. Look for third-party testing, GMP certification, and clean ingredient lists free from unnecessary fillers and artificial additives.
For liquid liposomal options, expect to refrigerate after opening and consume within the recommended timeframe. Capsule-based liposomal products generally have longer shelf lives and are more convenient for travel. Choose based on your lifestyle preferences and whether you value convenience or maximum absorption flexibility.
Frequently Asked Questions
What is liposomal magnesium and how is it different from regular magnesium?
Liposomal magnesium encapsulates the mineral inside tiny phospholipid spheres (liposomes) that protect it through the digestive tract and facilitate direct cellular absorption. This delivery method can significantly improve bioavailability compared to standard magnesium capsules or tablets, which must survive stomach acid and compete with other nutrients for absorption in the intestines.
How much liposomal magnesium should I take daily?
Most adults benefit from 200-400mg of elemental magnesium daily, though individual needs vary based on diet, activity level, and health conditions. Because liposomal delivery improves absorption, you may need less than you would with a standard magnesium supplement. Start with the manufacturer’s recommended dose and adjust based on how you feel.
When is the best time to take liposomal magnesium?
Many people prefer taking liposomal magnesium in the evening since it supports relaxation and sleep. However, it can be taken at any time of day. For forms that support cognitive function (like magnesium L-threonate), morning or early afternoon may be preferable. Liposomal magnesium can be taken with or without food due to its enhanced absorption profile.
Are there any side effects of liposomal magnesium?
Liposomal magnesium is generally well-tolerated and less likely to cause GI side effects than standard magnesium supplements. However, taking more than the recommended dose can still cause loose stools or diarrhea. People with kidney disease should consult their healthcare provider before supplementing with magnesium, as impaired kidney function can affect magnesium clearance.
Can I take liposomal magnesium with other supplements?
Liposomal magnesium pairs well with vitamin D3, vitamin K2, zinc, and B vitamins, which act as cofactors in magnesium metabolism. Avoid taking magnesium at the same time as calcium supplements or antibiotics, as they can interfere with absorption. Space magnesium and calcium supplements at least 2 hours apart for optimal uptake of both minerals.
How long does it take for liposomal magnesium to work?
Some benefits like improved relaxation and sleep quality may be noticeable within the first week of consistent use. However, correcting a magnesium deficiency typically takes 4-6 weeks of regular supplementation. Liposomal delivery may accelerate results compared to standard forms due to improved absorption rates, but individual responses vary.
