Best Molybdenum Supplements (2026)

Molybdenum is an essential trace mineral that most people have never heard of — yet it plays a critical role in enzyme activation, sulfite metabolism, and detoxification. As a cofactor for enzymes like sulfite oxidase, xanthine oxidase, and aldehyde oxidase, molybdenum helps the body break down harmful sulfites, purines, and aldehydes that would otherwise accumulate and cause problems.

While molybdenum deficiency is rare due to its presence in legumes, grains, and leafy vegetables, supplementation is increasingly popular among those with sulfite sensitivity, candida overgrowth concerns, and individuals following detoxification protocols. The best molybdenum supplements use chelated glycinate forms for optimal absorption. Here are the top options available.

Comparison of the Best Molybdenum Supplements

Product	Dose	Form	Count	Best For
Thorne Molybdenum Glycinate	1 mg (1,000 mcg)	Glycinate Chelate Capsules	60 Capsules	Best overall premium option
Seeking Health Molybdenum	500 mcg	Glycinate Chelate Capsules	90 Capsules	Best for sulfite sensitivity
Carlson Moly-B	500 mcg	Glycinate Chelate Tablets	100 Tablets	Best value from a trusted brand
Piping Rock Molybdenum	500 mcg	Chelated Amino Acid Capsules	200 Capsules	Best high-count budget option
Horbaach Molybdenum	500 mcg	Amino Acid Chelate Capsules	200 Capsules	Best value per capsule
KAL Molybdenum Chelated	250 mcg	Chelated Tablets	100 Tablets	Best moderate-dose option
Kirkman Molybdenum	100 mcg	Glycinate Capsules	100 Capsules	Best hypoallergenic low-dose
Biotics Research Mo-Zyme Forte	150 mcg	Tablets	100 Tablets	Best practitioner-grade option

Detailed Product Reviews

1. Thorne Molybdenum Glycinate — Best Overall Molybdenum Supplement

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Thorne has earned its reputation as one of the most trusted supplement brands in the practitioner channel, and their molybdenum glycinate exemplifies their commitment to quality. The well-absorbed glycinate chelate form delivers 1,000 mcg (1 mg) per capsule, making it one of the higher-potency options available for those who need robust sulfite metabolism support.

This key trace mineral promotes liver detoxification and particularly benefits sulfite-sensitive individuals. Thorne’s formulation contains no unnecessary fillers or additives, and every batch is tested for quality, safety, and efficacy with potency guaranteed through the expiration date. Trusted by healthcare practitioners and U.S. National Teams for over 30 years.

Pros:

• Highly absorbable molybdenum glycinate chelate
• 1,000 mcg dose for therapeutic-level support
• No unnecessary fillers or additives
• Trusted by practitioners and professional athletes for 30+ years

Cons:

• Only 60 capsules per bottle
• 1,000 mcg may be more than some users need

Best for: Those seeking premium, practitioner-grade molybdenum for liver detox and sulfite metabolism

2. Seeking Health Molybdenum — Best for Sulfite Sensitivity

Developed by Dr. Ben Lynch, a naturopathic physician known for his work on methylation and nutrigenomics, Seeking Health’s molybdenum is specifically formulated to support sulfite metabolism. The 500 mcg molybdenum glycinate chelate per capsule supports healthy iron utilization, liver function, and kidney waste removal.

The formula is exceptionally clean — free from GMOs, gluten, eggs, fish, shellfish, tree nuts, peanuts, wheat, sesame, and soy. With 90 capsules per bottle providing a three-month supply, this offers strong value from a brand that prioritizes quality at every step from research to packaging.

Pros:

• Formulated by Dr. Ben Lynch for targeted sulfite support
• 500 mcg glycinate chelate — well-tolerated dose
• Free from 10+ common allergens
• 90-capsule three-month supply

Cons:

• Premium pricing for the practitioner-channel brand
• May be unnecessary for those without sulfite sensitivity

Best for: Those with sulfite sensitivity or following methylation-focused health protocols

3. Carlson Moly-B — Best Value from a Trusted Brand

Carlson’s Moly-B delivers 500 mcg of molybdenum glycinate chelate in vegetarian tablets, with 100 per bottle for over three months of daily supplementation. The family-owned company has manufactured high-quality supplements for over 50 years, bringing deep expertise in mineral formulation.

The glycinate chelate form supports both metabolism and enzyme activation. Carlson’s commitment to quality includes rigorous testing protocols and clean formulations without unnecessary additives. The 300-tablet option is also available for those wanting an even longer supply.

Pros:

• 500 mcg glycinate chelate at a competitive price
• 100-tablet supply (300-count also available)
• Family-owned company with 50+ years of expertise
• Vegetarian formula

Cons:

• Tablet form rather than capsule
• Contains maltodextrin as minor ingredient

Best for: Those wanting reliable molybdenum from an established family brand at a fair price

4. Piping Rock Molybdenum — Best Budget High-Count Option

Piping Rock excels at delivering substantial capsule counts at accessible prices, and their molybdenum supplement is no exception. With 200 quick-release capsules at 500 mcg each, this provides over six months of daily supplementation. The molybdenum is provided in chelated form, bonded to an amino acid for enhanced absorption.

Lab-tested for purity and potency, non-GMO, and gluten-free. The quick-release capsule design supports faster nutrient delivery compared to standard capsules. For those on a budget who want consistent daily molybdenum supplementation, this is hard to beat.

Pros:

• 200 capsules for an outstanding 6+ month supply
• Chelated amino acid form
• Lab-tested for purity and potency
• Quick-release capsule design

Cons:

• Less brand prestige than practitioner brands
• Basic formula without additional cofactors

Best for: Budget-conscious users who want maximum supply at minimum cost

5. Horbaach Molybdenum — Best Value Per Capsule

Horbaach delivers 200 capsules of amino acid chelated molybdenum at 500 mcg per serving — matching Piping Rock’s count while offering competitive pricing. The quick-release capsules are gluten-free, non-GMO, and made without artificial color, flavor, sweetener, or preservatives.

Horbaach’s formula provides 1,111% of the daily value per serving, ensuring robust support for enzyme activation and sulfite metabolism. A practical, no-frills option for daily trace mineral supplementation.

Pros:

• 200-capsule supply at very competitive pricing
• 500 mcg amino acid chelate
• Free from artificial ingredients
• Quick-release capsule format

Cons:

• Newer brand with less established track record
• No advanced chelation technology like glycinate

Best for: Those wanting maximum capsule count at the lowest possible price

6. KAL Molybdenum Chelated — Best Moderate-Dose Option

KAL offers a more moderate 250 mcg dose that may suit those who want the benefits of molybdenum supplementation without the higher doses found in most products. The chelated form supports absorption, and the 100-tablet supply provides over three months of daily use. KAL backs the product with their 60-day satisfaction guarantee.

This is an ideal option for those new to molybdenum supplementation or those who want to combine it with a multivitamin that already contains some molybdenum, avoiding excessive total intake.

Pros:

• Moderate 250 mcg dose for conservative supplementation
• Chelated form for absorption
• 100-tablet supply
• 60-day satisfaction guarantee

Cons:

• Lower dose may not be sufficient for therapeutic use
• Contains rice flour and magnesium stearate

Best for: Those seeking a moderate dose for daily maintenance or to complement existing supplementation

7. Kirkman Molybdenum — Best Hypoallergenic Low-Dose

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Kirkman specializes in hypoallergenic supplements, and their 100 mcg molybdenum glycinate is the cleanest low-dose option on the market. Free from milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame with plant-based capsules and Ultra Tested® quality assurance. Gluten and casein free.

At 100 mcg, this sits closer to the daily adequate intake levels and is appropriate for those who want gentle support without high therapeutic doses. Kirkman’s reputation for purity makes this particularly suitable for individuals with chemical sensitivities or those following elimination protocols.

Pros:

• Lowest dose available at 100 mcg for gentle supplementation
• Hypoallergenic — free from all major allergens
• Ultra Tested® quality assurance
• Plant-based capsules, gluten and casein free

Cons:

• 100 mcg may be insufficient for those with active sulfite sensitivity
• Higher price per unit than budget brands

Best for: Those with multiple sensitivities who need the gentlest, cleanest molybdenum supplement available

8. Biotics Research Mo-Zyme Forte — Best Practitioner-Grade Molybdenum

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Biotics Research is a practitioner-only brand that delivers 150 mcg of molybdenum per tablet in their Mo-Zyme Forte formula. The company is known for whole food-based supplement delivery systems and rigorous quality controls that meet or exceed pharmaceutical-grade standards. Each bottle contains 100 tablets.

Mo-Zyme Forte supports liver detoxification, healthy metabolism, and antioxidant function. The moderate 150 mcg dose makes it easy to fine-tune intake by adjusting the number of tablets daily. Typically available through healthcare practitioners or select retailers.

Pros:

• Practitioner-grade quality from Biotics Research
• 150 mcg dose allows flexible dosing
• Supports liver detox and metabolism
• 100-tablet supply

Cons:

• May be harder to find than consumer brands
• Tablet format only

Best for: Those working with a healthcare practitioner who recommends Biotics Research products

How to Choose a Molybdenum Supplement

Molybdenum glycinate chelate is the preferred form for most users, offering superior absorption compared to molybdenum amino acid chelates or molybdenum from sodium molybdate. Glycinate chelation bonds the mineral to the amino acid glycine, facilitating transport across the intestinal wall and reducing the potential for digestive discomfort.

Dosage selection depends largely on your reason for supplementing. For general daily maintenance, 100-250 mcg is typically sufficient. Those dealing with sulfite sensitivity, candida die-off symptoms, or active detoxification may benefit from 500-1,000 mcg under practitioner guidance. The tolerable upper intake level for adults is 2,000 mcg daily, but most people do well with far less.

Molybdenum works closely with other trace minerals and can affect copper metabolism — high molybdenum intake may lower copper levels. If supplementing long-term with molybdenum, consider monitoring copper status. For those interested in comprehensive liver cleanse support, molybdenum pairs well with NAC, milk thistle, and other liver-supportive nutrients. Those dealing with sulfite reactions may also benefit from exploring detox supplements for a more complete protocol.

Frequently Asked Questions

What does molybdenum do in the body?

Molybdenum serves as a cofactor for several important enzymes: sulfite oxidase (converts harmful sulfites to sulfate), xanthine oxidase (involved in purine metabolism and uric acid production), and aldehyde oxidase (breaks down aldehydes and certain drugs). Without adequate molybdenum, these enzymes cannot function properly, potentially leading to sulfite buildup and impaired detoxification.

Who should consider taking molybdenum supplements?

Molybdenum supplementation may benefit those with sulfite sensitivity (reacting to wine, dried fruits, or preserved foods), individuals experiencing symptoms of candida die-off (which produces acetaldehyde), and those following detoxification protocols. People on very restrictive diets that exclude legumes and grains may also benefit from supplementation.

Can molybdenum help with sulfite sensitivity?

Yes, molybdenum is a critical cofactor for sulfite oxidase, the enzyme responsible for converting sulfites to the less harmful sulfate form. Many practitioners recommend molybdenum supplementation for individuals who experience reactions to sulfite-containing foods and beverages. Typical therapeutic doses for sulfite sensitivity range from 250-500 mcg daily.

What are the symptoms of molybdenum deficiency?

True molybdenum deficiency is extremely rare but can cause rapid heart rate, rapid breathing, headache, night blindness, and in severe cases, sulfite toxicity leading to neurological damage. Subclinical deficiency may manifest as increased sulfite sensitivity, poor aldehyde detoxification, and elevated uric acid levels. Most people obtain sufficient molybdenum from a varied diet.

Are there interactions between molybdenum and other minerals?

Molybdenum can affect copper metabolism — high molybdenum intake may reduce copper absorption and increase copper excretion. Those supplementing with molybdenum long-term should be aware of this interaction and may need to monitor copper levels. Conversely, very high copper intake can reduce molybdenum utilization. Balancing trace minerals is important for optimal health.

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