Best Omega-3 for Heart Health (2026)
Omega-3 fatty acids — particularly EPA and DHA — are among the most well-researched nutrients for cardiovascular support. They help maintain healthy triglyceride levels, support normal blood pressure, and promote overall heart function. Whether from fish oil, algae, or krill, the right omega-3 supplement can be a meaningful addition to a heart-healthy routine. These are the best options available right now.
Quick Comparison
| Product | EPA + DHA Per Serving | Form | Best For | Rating |
|---|---|---|---|---|
| PYM Omega-3 | DHA + EPA blend | Softgels | Best Overall | 9.4/10 |
| Vital Nutrients Ultra Pure Fish Oil 700 | 700 mg Omega-3 | Softgels | Best Premium | 9.3/10 |
| NATURELO Vegan DHA | DHA from Algae | Softgels | Best Vegan | 9.2/10 |
| NATURELO Burpless Omega 3 | 1,100 mg Omega-3 | Softgels | Best Burpless | 9.1/10 |
| Pink Stork Omega-3 DHA | 540 mg Fish Oil | Softgels | Best for Women | 9.0/10 |
| Nordic Naturals Ultimate Omega | 1,280 mg Omega-3 | Soft Gels | Best High-Potency | 9.3/10 |
| Viva Naturals Triple Strength Omega-3 | 2,500 mg Fish Oil | Softgels | Best Value | 9.1/10 |
1. PYM Omega-3 for Mood and Emotional Support – Best Overall
- Prepare Your Mind: PYM Mood Omegas are formulated by neuroscientists and nutritional psychiatrists to support feelings of brain fog, nerves and overall mood.
- Mindful Blend Of Ingredients: These non-GMO capsules are made with DHA, to support feelings of brain fog, as well as EPA to support lower inflammation.
- Sustainably Sourced: Our gluten-free omegas are sustainably sourced from deep sea, cold water sardines and mackerel in Chile. With an added touch of citrus, you'll experience no aftertaste. Made in the USA.
- Everyday Solution To Everyday Stress: Fatty acids can be taken at any time of day, but some research shows additional benefits if you take them with a full meal and before bed.
- A Mindful Mission: PYM’s mission is to provide natural and effective mental hygiene products to promote self-care and mental well-being. PYM prepares your mind to produce the naturally occurring neurotransmitters that help you feel like yourself again.
PYM’s Omega-3 delivers a well-balanced EPA and DHA profile designed specifically to support both cardiovascular and emotional well-being.
This 60-count softgel bottle provides omega-3 fatty acids with meaningful amounts of both EPA and DHA — the two fatty acids most studied for heart health benefits. PYM formulates with quality sourcing and clean ingredients, and the dual benefit of mood and heart support makes it a versatile daily supplement. The softgels are easy to swallow and the formula is designed to minimize fishy aftertaste.
- Pros:
- Balanced EPA and DHA for heart and mood support
- Clean formulation from a trusted brand
- 60-count bottle for a full month supply
- Cons:
- Lower total omega-3 per serving than some competitors
- Premium price point for the serving count
Best for: Users who want a clean omega-3 supplement that supports both heart health and emotional balance.
2. Vital Nutrients Ultra Pure Fish Oil 700 – Best Premium
- Premium Omega-3 Fish Oil Supplements: Support your heart, brain, and joint health, plus promote healthy triglyceride levels.* Ultra Pure Fish Oil 700 offers a potent concentration of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), key omega-3 fatty acid supplements essential for optimal well-being
- No Fish Oil Burps or Reflux: Enjoy our sustainably sourced, wild-caught fish oil supplement rich in omega-3 fatty acids, delivering 720mg of EPA and 480mg of DHA in two softgels. Enhanced with a pleasant lemon flavor, it eliminates the common "fishy" aftertaste associated with other fish oil supplements*
- Clean Formula: Non-GMO. Made without artificial fillers, coatings, binders, or colors.
- Quality You Can Rely on: Our rigorous quality assurance program includes third-party independent laboratory testing of raw ingredients and finished products for purity and potency to ensure what’s on the label is in the bottle.
- Trusted by Healthcare Practitioners Worldwide: Vital Nutrients was founded 30 years ago by practitioners who set out to make a positive and lasting impact on the health of people and planet. Today, our premium line of clinically relevant, pure, clean-label formulas is trusted by healthcare practitioners and health-conscious consumers worldwide
Vital Nutrients delivers a practitioner-grade fish oil with 700 mg of omega-3 per softgel, setting a high bar for purity and potency.
This supplement is sustainably sourced and undergoes rigorous testing for heavy metals, PCBs, and other contaminants. With 700 mg of total omega-3 per softgel, it provides a clinically meaningful dose of EPA and DHA in each serving. Vital Nutrients is a brand commonly recommended by healthcare practitioners, which speaks to its quality standards. The formula supports heart, brain, and joint health, making it a strong all-around omega-3 choice for cardiovascular-focused users.
- Pros:
- 700 mg omega-3 per softgel — high potency
- Practitioner-grade quality with rigorous testing
- Sustainably sourced fish oil
- Cons:
- Higher price point reflects premium quality
- Larger softgel size may be harder to swallow
Best for: Health-conscious users who want practitioner-recommended, ultra-pure fish oil for heart support.
3. NATURELO Vegan DHA – Best Vegan Option
- VEGAN DHA SUPPLEMENT: Sourced from Algae, our DHA softgels are a vegan and vegetarian friendly algae omega 3 supplement to get the health benefits of Omega-3 that your body needs to function and stay healthy
- POWERFUL HEALTH BENEFITS: Long-chain Omega-3 fatty acids like DHA from vegan omega 3 support heart health, joint function & mobility, eye/macular wellness, skin smoothness, muscle recovery, healthy brain function for cognition, focus, mood
- FOR PRENATAL HEALTH: DHA is an essential nutrient for pregnant women looking to nurture their baby's healthy brain and eye development
- PREMIUM QUALITY: Natural formula of Docosahexaenoic Acid (DHA), an omega 3 essential acid from marine algae. Non-GMO, Vegan, no fish and no fishy burps. Contains no coloring, flavoring, or preservatives of any kind
- FROM NATURE WITH LOVE: We believe the best nutrition comes from nature, not from a lab. We formulate our supplements using only the cleanest, most bioavailable ingredients whenever possible to harness the power of plants for whole food nutrition
NATURELO’s algae-based DHA delivers plant-sourced omega-3 without any fish, making it the top choice for vegans and vegetarians who prioritize heart health.
Each bottle contains 120 vegan softgels with DHA sourced from sustainably harvested algae. Algae is where fish actually get their omega-3, so going directly to the source provides the same beneficial fatty acid without the environmental concerns of fishing. The formula supports brain, heart, and eye health. NATURELO is known for using whole-food-based ingredients and avoiding synthetic fillers, and this product maintains that standard.
- Pros:
- 100% plant-based DHA from algae — no fish
- 120 softgels per bottle — excellent supply
- Sustainably sourced and environmentally friendly
- Cons:
- Lower EPA content compared to fish-based omega-3s
- Cost per serving is higher than conventional fish oil
Best for: Vegans, vegetarians, and anyone who wants sustainable, plant-based omega-3 for cardiovascular support.
4. Nordic Naturals Ultimate Omega – Best High-Potency
- Why omega-3s - Research shows that the essential fatty acids EPA & DHA in fish oil support heart, brain, eye function*
- Doctor-recommended formula - Nordic Naturals Ultimate Omega features high concentration omega-3 fish oil in soft gels; This formula meets the daily recommended dose suggested by the American Heart Association to support heart function*
- Better absorption, better taste, no fishy burps - All of our omega-3 fish oil concentrates are in the triglyceride molecular form (the form naturally found in fish) for optimal absorption
- Purity guaranteed - Every batch of Nordic Naturals fish oil is crafted from fresh, wild-caught, omega-rich fish
- ETHICAL INNOVATION - Nordic Naturals is proud to be at the forefront of sustainable & ethical practices in the natural products industry. Through science & innovation, we are committed to delivering safe, effective nutrients to support foundational wellness.
Nordic Naturals Ultimate Omega is one of the most trusted fish oil supplements in the world, delivering 1,280 mg of omega-3 per serving in highly absorbable triglyceride form.
This doctor-recommended formula provides concentrated EPA and DHA in the superior triglyceride molecular form, which research shows is better absorbed than the ethyl ester form used by many competitors. The lemon-flavored soft gels are designed to eliminate fishy burps and aftertaste. Nordic Naturals tests every batch for environmental toxins, including heavy metals, dioxins, and PCBs, exceeding international pharmaceutical standards. Each bottle contains 90 soft gels for a 45-day supply.
- Pros:
- 1,280 mg omega-3 per serving — high potency
- Triglyceride form for superior absorption
- Award-winning brand with exceptional purity standards
- Cons:
- Premium pricing
- Two soft gels per serving adds up at higher doses
Best for: Users who want a high-potency, highly absorbable omega-3 from an industry-leading brand.
5. NATURELO Burpless Omega 3 Fish Oil – Best Burpless Formula
- NO BURPS, FRESH FLAVOR: The fish oil supplements burpless formula works to prevent a fishy smell or fishy aftertaste, maintaining freshness with a hint of lemon. Omega 3 fish oil is burpless, giving you comfort and great taste.
- HIGH ABSORPTION: The fish oil omega 3 supplements use the Triglyceride form of Omega-3 to support absorption. Each softgel packs a potent 1100 mg of Omega-3, requiring only one capsule per day to help meet your omega-3 DHA and EPA fatty acid needs.
- PURE AND SUSTAINABLE: This omega-3 fish oil is sourced and purified in the United States from sustainable, wild-caught Alaskan Pollock. Advanced molecular distillation techniques are used, creating high quality fish oil omega 3 supplements.
- HEALTH BENEFITS: Fish oils omega 3 fatty acids can support several health benefits including heart, brain, eye, and joint health function. This Omega-3 fish oil supplement can help fill the omega 3 fatty acids nutrient gap if your diet lacks fish and other dietary sources of omega-3 fats.
- EXTENDED SUPPLY: One bottle offers a 2-month supply, with our liquid omega 3 fish oil formula requiring only one softgel per day.
NATURELO’s triglyceride-form fish oil delivers 1,100 mg of omega-3 per serving with an enteric coating that eliminates fishy burps and aftertaste.
This supplement uses the triglyceride form of omega-3 — the same form found naturally in fish — which is more bioavailable than cheaper ethyl ester alternatives. The enteric coating ensures the softgel dissolves in the intestine rather than the stomach, virtually eliminating the fishy burps that drive many people away from fish oil supplements. The formula provides a strong EPA and DHA profile for heart, brain, and joint support, and NATURELO’s commitment to clean ingredients means no artificial fillers or synthetic additives.
- Pros:
- 1,100 mg omega-3 in triglyceride form
- Enteric-coated for truly burpless experience
- No artificial ingredients or synthetic fillers
- Cons:
- Slightly smaller serving count per bottle
- Costs more than basic ethyl ester fish oils
Best for: Users who have avoided fish oil due to fishy aftertaste and want a genuinely burpless option.
6. Pink Stork Omega-3 DHA – Best for Women
- Pink Stork Prenatal DHA features two omega 3 fatty acid supplements - 325 mg DHA and 130 mg EPA from sustainably sourced fish. Add to your prenatal ritual to support maternal health and fetal development; take one soft gel daily alongside your prenatal vitamins. Packaging May Vary
- An omega 3 supplement is a pregnancy must-have! These essential fatty acids are depleted from a pregnant woman's body, since your developing baby is using them to support neurological, cognitive, and visual development throughout each trimester. DHA is essential for the development of your baby's brain and retina throughout the third trimester and the first few years of their life.
- Pink Stork DHA and EPA omega 3 supplement is crucial for postnatal wellness! Our DHA supplements help ease postpartum brain fog (hello, new mom brain!) and postpartum hormone balance -- and provide lactation support as benefits pass through breast milk to nursing babies.
- Our DHA omega 3 fish oil comes from sustainably sourced fish. Clean, effective, high-quality supplements to support you through this new chapter of life! Take alongside any Pink Stork Prenatal Vitamin, fertility supplements for women, or postnatal vitamins. We have you covered through each stage of life!
- We are Women-Owned and Women-Run! Our founder and CEO, Amy Suzanne, is a mom of 6 children and knows how important it is to give new moms products you can trust. Over 80% of our employees are women, and we create clean, trusted, and effective products for every stage of your journey. We are on a mission to provide women with hope and positively impact everyone who comes in contact with Pink Stork.
Pink Stork formulates this omega-3 with 540 mg of fish oil including targeted DHA levels, designed specifically for women’s cardiovascular and overall health.
While originally formulated for prenatal and postpartum support, this fish oil supplement provides EPA and DHA that benefit heart health for women at any stage of life. DHA in particular supports cardiovascular function, brain health, and healthy inflammatory response. The softgels are smaller than typical fish oil capsules, making them easier to swallow. Pink Stork is a women-focused brand with strong quality standards and transparent ingredient sourcing.
- Pros:
- Formulated specifically for women’s health needs
- Smaller, easier-to-swallow softgels
- Strong DHA content for heart and brain support
- Cons:
- Lower total omega-3 per serving than high-potency options
- Marketing skews prenatal, but benefits are universal
Best for: Women who want an omega-3 supplement tailored to their health needs with a focus on DHA.
7. Viva Naturals Triple Strength Omega-3 – Best Value
- Triple strength omega-3 fish oil - Our fish oil for men and women delivers a high-potency dose of omega-3 with each serving providing 2,500 mg of fish oil, including 1,500 mg EPA, 570 mg DHA and 50 mg DPA
- Omega-3 for heart, brain, skin & eye health* - Science has shown that not only do the omega-3s in fish oil offer cardiovascular support for men and women, but they also support brain health, skin and eye health*
- Purified to reduce mercury - Using a combination of fish (sardines, anchovies and mackerel), our fish oil is purified to reduce PCBs, dioxins, furans and mercury to ensure levels are below IFOS set limits of ≤45 ppb, ≤ 1 ppt and ≤ 0.1 ppm respectively
- For greater absorption - The omega-3 fatty acids in our fish oil capsules are delivered in re-esterified triglyceride form. Triglycerides have been shown to be more easily absorbed by your body
- Quality you can trust - Made with wild caught fish using sustainable fishing practices. Our fish oil softgels are IFOS Certified and Labdoor Certified for quality, purity and potency, and are also gluten-free, non-GMO and pescatarian-friendly
Viva Naturals packs 2,500 mg of fish oil with 1,500 mg EPA and 570 mg DHA per serving into a highly absorbable triglyceride form — all at a competitive price.
This triple-strength formula is one of the most potent options on the market, delivering over 2,000 mg of combined EPA and DHA per serving. The fish oil is in re-esterified triglyceride form, which offers up to 70% better absorption than standard ethyl esters. Sourced from wild-caught fish (sardines, anchovies, and mackerel) and purified to reduce mercury, PCBs, and other contaminants. The 180-softgel bottle provides a 90-day supply, making it an exceptional value for the potency delivered.
- Pros:
- 2,500 mg fish oil with 1,500 mg EPA + 570 mg DHA
- Re-esterified triglyceride form for superior absorption
- 180 softgels — 90-day supply at an excellent price
- Cons:
- Two softgels per serving
- Larger softgel size
Best for: Users who want maximum omega-3 potency at the best price per serving.
8. Vital Nutrients Ultra Pure Fish Oil 700 (200 Softgels) – Best Bulk Option
- Premium Omega-3 Fish Oil Supplements: Support your heart, brain, and joint health, plus promote healthy triglyceride levels.* Ultra Pure Fish Oil 700 offers a potent concentration of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), key omega-3 fatty acid supplements essential for optimal well-being
- No Fish Oil Burps or Reflux: Enjoy our sustainably sourced, wild-caught fish oil supplement rich in omega-3 fatty acids, delivering 720mg of EPA and 480mg of DHA in two softgels. Enhanced with a pleasant lemon flavor, it eliminates the common "fishy" aftertaste associated with other fish oil supplements*
- Clean Formula: Non-GMO. Made without artificial fillers, coatings, binders, or colors.
- Quality You Can Rely on: Our rigorous quality assurance program includes third-party independent laboratory testing of raw ingredients and finished products for purity and potency to ensure what’s on the label is in the bottle.
- Trusted by Healthcare Practitioners Worldwide: Vital Nutrients was founded 30 years ago by practitioners who set out to make a positive and lasting impact on the health of people and planet. Today, our premium line of clinically relevant, pure, clean-label formulas is trusted by healthcare practitioners and health-conscious consumers worldwide
The same practitioner-grade formula as the standard size, but in a 200-softgel bottle that provides months of consistent cardiovascular support.
This larger bottle of Vital Nutrients Ultra Pure Fish Oil 700 delivers the same 700 mg of omega-3 per softgel with the same rigorous purity testing. The 200-count size is ideal for users who have already found their preferred omega-3 and want to buy in bulk to save money and avoid running out. Sustainably sourced and tested for contaminants, this is a set-it-and-forget-it heart health staple.
- Pros:
- 200 softgels — excellent long-term value
- Same practitioner-grade quality in bulk format
- Sustainably sourced with comprehensive testing
- Cons:
- Higher upfront cost for the larger bottle
- Same large softgel size
Best for: Long-term omega-3 users who want premium quality in a bulk-sized bottle.
How to Choose the Best Omega-3 for Heart Health
The most important factor is the combined EPA and DHA content per serving — not the total fish oil amount. Many budget brands advertise 1,000 mg of fish oil but deliver only 300 mg of actual omega-3 fatty acids. For meaningful cardiovascular benefits, look for supplements providing at least 500 mg of combined EPA and DHA per daily dose. The American Heart Association generally suggests 1 gram of EPA + DHA daily for people with documented heart disease, and higher amounts for elevated triglycerides.
The molecular form of omega-3 affects absorption. Triglyceride-form fish oil is absorbed significantly better than ethyl ester form, though it typically costs more. Re-esterified triglycerides offer the best of both worlds — high concentration and high bioavailability. Algae-based omega-3 is an excellent alternative for vegans, though it tends to be heavier on DHA than EPA.
Purity testing is non-negotiable. Quality fish oil supplements should be molecularly distilled and tested for mercury, PCBs, dioxins, and oxidation markers. Look for certifications from organizations like IFOS (International Fish Oil Standards), NSF, or USP. Brands that publish their Certificates of Analysis demonstrate the highest transparency.
Consider practical factors like burpless coatings, softgel size, and serving count. An enteric-coated or lemon-flavored softgel can dramatically improve compliance for people who have quit fish oil due to fishy aftertaste or burps.
Frequently Asked Questions
How much omega-3 should I take for heart health?
For general cardiovascular support, most health organizations recommend 250-500 mg of combined EPA and DHA daily. For people with elevated triglycerides, doses of 2,000-4,000 mg per day (under medical supervision) have been shown to reduce triglyceride levels significantly. It’s best to follow dosage guidance from a healthcare provider based on individual risk factors.
Is fish oil or algae oil better for heart health?
Both provide beneficial omega-3 fatty acids. Fish oil typically contains higher levels of both EPA and DHA, while algae oil is richer in DHA specifically. For heart health, EPA is particularly important for its anti-inflammatory and triglyceride-lowering effects. Fish oil is generally the better choice for cardiovascular support, though algae oil is an effective alternative for those who avoid animal products.
When is the best time to take omega-3 supplements?
Omega-3 supplements are best taken with a meal that contains fat, as dietary fat significantly improves absorption of EPA and DHA. There is no strong evidence that morning versus evening timing matters — consistency is more important than timing. Taking omega-3 with your largest meal of the day is a practical strategy.
Are there any side effects of omega-3 supplements?
Common side effects include fishy burps, mild nausea, and loose stools — most of which can be minimized by choosing enteric-coated softgels and taking them with food. At very high doses (above 3,000 mg daily), omega-3 may have a mild blood-thinning effect. People on anticoagulant medications should consult a healthcare provider before supplementing.
How long does it take for omega-3 to improve heart health markers?
Triglyceride reductions can typically be measured within 2-4 weeks of consistent supplementation at effective doses. Other cardiovascular benefits, such as improvements in blood vessel function and inflammatory markers, may take 8-12 weeks to become measurable. Long-term daily use produces the most significant and sustained cardiovascular benefits.
Can I get enough omega-3 from food alone?
It is possible if you eat fatty fish (salmon, mackerel, sardines, herring) at least twice per week. However, most people in Western diets fall well short of recommended omega-3 intake. Supplementation bridges the gap reliably and consistently, which is why it remains one of the most commonly recommended supplements by cardiologists and primary care providers.
