Best Pterostilbene Supplements (2026)

Pterostilbene is a naturally occurring polyphenol found primarily in blueberries and closely related to resveratrol—but with significantly better bioavailability. Research links pterostilbene to healthy aging, cardiovascular support, cognitive function, and antioxidant protection. Here are the top pterostilbene supplements for longevity-focused supplementation.

Quick Comparison

Product	Dose per Serving	Form	Best For	Rating
Extra Strength Pterostilbene (CC)	150 mg	Capsules	Best Overall	4.5/5
Double Wood Pterostilbene	100 mg	Capsules	Best Value	4.5/5
NusaPure Pterostilbene	150 mg	Veg Capsules	Best High-Count Bottle	4.4/5
Sunergetic Pterostilbene Complex	100 mg (+ Resveratrol + Quercetin)	Capsules	Best Combination Formula	4.4/5
Pterostilbene with Trans-Resveratrol	200 mg	Capsules	Most Potent	4.4/5
Pterostilbene 150mg (Ref)	150 mg	Capsules	Best 3-Month Supply	4.3/5
PRISTINE’S Pterostilbene	100 mg	Capsules	Best Budget Pick	4.3/5

1. Extra Strength Pterostilbene – Best Overall

This vegan-friendly 150 mg pterostilbene supplement delivers a potent dose in a clean formula designed for daily longevity support.

Each capsule provides 150 mg of pterostilbene—50% more than standard 100 mg products—in a vegan-friendly capsule format. The extra-strength dosing means one capsule per day provides optimal antioxidant and anti-aging support without the need for multiple pills. The formula is designed for healthy aging, cognitive support, and cardiovascular health. Manufactured with quality-focused standards, this supplement delivers a straightforward, single-ingredient approach to pterostilbene supplementation.

• Pros:
• 150 mg potent dose in a single capsule
• Vegan-friendly formulation
• One-capsule-per-day convenience

• Cons:
• Single-ingredient formula without complementary antioxidants
• Smaller brand awareness compared to Double Wood or NOW

Best for: Users wanting a straightforward, potent pterostilbene supplement at 150 mg per capsule

2. Double Wood Pterostilbene – Best Value

Double Wood delivers a well-tested 100 mg pterostilbene from one of the most trusted names in the nootropics and longevity supplement space.

Each bottle contains 60 capsules with 100 mg of pterostilbene per capsule, providing a one- to two-month supply depending on dosing. Double Wood Supplements has built a strong reputation in the nootropics community for quality, transparency, and value. The product is manufactured in the USA from globally sourced ingredients, non-GMO, and gluten-free. Each batch is rigorously third-party tested for purity and potency. The clean ingredient list includes just pterostilbene in a gelatin capsule with microcrystalline cellulose and rice flour.

• Pros:
• Established, trusted brand in the longevity space
• Third-party tested for each batch
• Competitive pricing for proven quality

• Cons:
• 100 mg per capsule—lower than 150-200 mg alternatives
• Gelatin capsules not suitable for vegans

Best for: Anyone wanting a reliable, well-tested pterostilbene from a brand known for quality nootropics

3. NusaPure Pterostilbene 150 mg – Best High-Count Bottle

NusaPure offers the highest capsule count at 180 vegan capsules, providing a full six-month supply at one capsule daily.

Each capsule delivers 150 mg of pterostilbene (taking two capsules per the suggested serving provides 300 mg for those wanting higher doses). The 180-capsule bottle is one of the most generous counts available in the pterostilbene category, providing exceptional long-term value. The formula is non-GMO and vegan-friendly, using cellulose capsules. NusaPure focuses on delivering quality supplements at excellent value, and this product exemplifies that mission.

• Pros:
• 180 capsules per bottle—up to 6-month supply
• 150 mg per capsule at an affordable per-serving cost
• Vegan-friendly formulation

• Cons:
• Suggested serving is two capsules (300 mg), which may be excessive for some
• Contains silica and rice flour as inactive ingredients

Best for: Long-term pterostilbene users who want the best value over a multi-month supply

4. Sunergetic Pterostilbene Complex – Best Combination Formula

Sunergetic combines pterostilbene with resveratrol and quercetin for a triple-antioxidant formula targeting healthy aging from multiple pathways.

Each two-capsule serving provides 100 mg of natural-source trans-pterostilbene (Silbinol), 200 mg of resveratrol, and 100 mg of quercetin dihydrate. Silbinol is a standardized pterostilbene extract obtained from the heartwood and bark of the Pterocarpus marsupium tree—a more premium source than synthetic alternatives. The combination of all three polyphenols creates a synergistic antioxidant effect: pterostilbene and resveratrol target similar but complementary longevity pathways, while quercetin enhances absorption and provides additional anti-inflammatory support. Manufactured in an FDA-registered, GMP-certified facility.

• Pros:
• Synergistic triple-antioxidant formula
• Uses natural-source Silbinol pterostilbene
• 200 mg resveratrol adds significant longevity support

• Cons:
• Requires two capsules per serving
• Lower pterostilbene dose (100 mg) compared to single-ingredient products

Best for: Users who want a comprehensive polyphenol stack combining pterostilbene, resveratrol, and quercetin

5. Pterostilbene with Trans-Resveratrol 200 mg – Most Potent

This extra-strength formula delivers the highest pterostilbene dose per serving at 200 mg, enhanced with 98% pure trans-resveratrol.

Each two-capsule serving provides 200 mg of trans-pterostilbene naturally sourced from wild-harvested blueberries, plus 20 mg of 98% trans-resveratrol from Japanese knotweed. The 200-capsule bottle delivers an impressive 100 servings—making it one of the longest-lasting pterostilbene supplements available. The formula uses dual-action antioxidant protection from both trans-pterostilbene and trans-resveratrol for cellular recovery, brain function, and immune health support. The product is non-GMO, non-irradiated, and third-party lab tested for safety and potency. Free from soy, dairy, gluten, preservatives, wheat, fish, and tree nuts.

• Pros:
• Highest dose at 200 mg per serving
• 200 capsules per bottle—100 servings
• Naturally sourced from wild blueberries

• Cons:
• Requires two capsules per serving
• Resveratrol dose is modest at 20 mg

Best for: Users wanting the highest-potency pterostilbene supplement with maximum supply per bottle

6. Pterostilbene 150 mg Vegan Capsules – Best 3-Month Supply

A clean, once-daily 150 mg pterostilbene formulation in 180 vegan capsules for a full three- to six-month supply.

This supplement delivers 150 mg of pterostilbene per capsule with a simple, clean formulation designed for daily longevity support. The 180-capsule bottle provides either a three-month supply at two capsules daily or a full six-month supply at one capsule daily. The formula supports healthy aging, antioxidant protection, and cellular health. Made in the USA with non-GMO ingredients in a clean, easy-to-swallow capsule format.

• Pros:
• 180 capsules for extended multi-month use
• Clean 150 mg single-ingredient formula
• Made in the USA with non-GMO ingredients

• Cons:
• Fewer reviews than more established brands
• Single-ingredient approach may limit synergistic benefits

Best for: Users who want a generous capsule count for long-term, cost-effective pterostilbene supplementation

7. PRISTINE’S Pterostilbene 100 mg – Best Budget Pick

PRISTINE’S offers an accessible entry point into pterostilbene supplementation with a 60-day supply at a wallet-friendly price.

Each capsule delivers 100 mg of pterostilbene in a 60-count bottle providing a full two-month supply at one capsule daily. The formula emphasizes pterostilbene’s naturally high bioavailability—significantly better than resveratrol—for antioxidant, cognitive, and lung health support. This small-business brand focuses on delivering quality basics without premium pricing. The clean formulation makes it an ideal starting point for anyone curious about pterostilbene but not ready to commit to higher-priced options.

• Pros:
• Most affordable option for pterostilbene supplementation
• 60-day supply at one capsule daily
• High natural bioavailability

• Cons:
• 100 mg dose is the lowest on this list
• Smaller brand with limited track record

Best for: Budget-conscious buyers and first-time pterostilbene users wanting to try it affordably

8. Wellness Resources Pterostilbene – Best Natural Source

No products found.

Wellness Resources uses natural-source Silbinol trans-pterostilbene for a premium, single-ingredient formula from a trusted health brand.

Each capsule provides 100 mg of Silbinol, a trademarked natural-source trans-pterostilbene extract. Silbinol is considered one of the gold-standard pterostilbene ingredients, sourced from the heartwood of the Pterocarpus marsupium tree and standardized for consistent potency. The 60 veggie capsules provide a one- to two-month supply. Wellness Resources has a strong following among health-conscious consumers who value ingredient sourcing and formulation integrity. The product is non-GMO, vegan, and soy-free.

• Pros:
• Uses trademarked Silbinol natural-source pterostilbene
• Vegan veggie capsules
• Trusted brand with health-focused customer base

• Cons:
• 100 mg per capsule—lower than 150-200 mg alternatives
• Higher per-capsule cost than generic pterostilbene products

Best for: Users who want a premium, naturally sourced pterostilbene with trademarked ingredient verification

How to Choose the Best Pterostilbene Supplement

Pterostilbene doses in supplements typically range from 50 mg to 250 mg per serving. Research on cognitive benefits and metabolic health has used doses between 100 mg and 250 mg daily. For general antioxidant and longevity support, 100-150 mg daily is a solid starting point. Higher doses (200-250 mg) may be appropriate for those specifically targeting cardiovascular markers or blood sugar support, but starting lower and adjusting is always prudent.

The source of pterostilbene matters. Silbinol and other trademarked extracts from the Pterocarpus marsupium tree offer standardized, natural-source trans-pterostilbene with consistent potency. Blueberry-derived pterostilbene is another natural option. While synthetic pterostilbene can be effective, natural-source extracts are generally preferred for their established quality profiles and the additional presence of beneficial co-compounds.

Combination formulas that pair pterostilbene with resveratrol and quercetin can offer synergistic benefits. Pterostilbene and resveratrol activate similar longevity-associated pathways (including SIRT1 and AMPK) but through slightly different mechanisms, while quercetin enhances absorption and adds anti-inflammatory activity. However, if you want flexibility in dosing each compound individually, standalone pterostilbene products may be preferable.

As with any supplement, verify GMP-certified manufacturing, third-party testing, and a clean ingredient list free from unnecessary fillers and allergens. Vegans should look specifically for products using cellulose or hypromellose capsules, as many pterostilbene supplements use gelatin capsules by default.

Frequently Asked Questions

What is pterostilbene and how is it different from resveratrol?

Pterostilbene is a polyphenol antioxidant naturally found in blueberries, grapes, and certain tree barks. It is chemically a dimethylated version of resveratrol, which gives it significantly better bioavailability—up to four times higher oral absorption. Both compounds activate similar longevity-related pathways, but pterostilbene’s superior bioavailability means effective results can be achieved at lower doses.

How much pterostilbene should I take daily?

Most research and supplement manufacturers recommend 100 to 250 mg of pterostilbene daily. For general antioxidant and longevity support, 100-150 mg once daily is standard. For specific health targets like blood sugar or cholesterol support, doses of 150-250 mg have been used in clinical research. Some users take pterostilbene in combination with resveratrol, in which case lower doses of each may be sufficient.

When is the best time to take pterostilbene?

Pterostilbene can be taken at any time of day, though taking it with a meal containing some fat may improve absorption since it is a fat-soluble compound. Many users prefer taking it in the morning as part of their daily supplement routine. Consistency matters more than timing—taking it at the same time each day helps maintain steady levels.

Are there any side effects of pterostilbene?

Pterostilbene is generally well tolerated at recommended doses. Some individuals may experience mild digestive upset. Those taking medications for blood sugar or cholesterol management should consult a healthcare provider, as pterostilbene may have additive effects with these medications. Pregnant and nursing women should avoid pterostilbene supplementation due to limited safety data in these populations.

Can I take pterostilbene with other supplements?

Yes, pterostilbene pairs well with several longevity-focused supplements. Common combinations include resveratrol (for complementary polyphenol activity), quercetin (for enhanced absorption and anti-inflammatory support), NMN or NR (for NAD+ pathway synergy), and CoQ10 (for mitochondrial support). Pterostilbene is also a component of the popular NR + pterostilbene combination found in some NAD+ supplement formulations.

How long does it take for pterostilbene to work?

As an antioxidant, pterostilbene begins working at the cellular level immediately after absorption. However, noticeable effects on energy, cognitive clarity, and metabolic markers typically develop over two to four weeks of consistent daily use. Changes in blood markers like cholesterol or blood sugar may take four to eight weeks to become measurable. Long-term longevity benefits are cumulative and best supported by ongoing daily supplementation.