Best Sulforaphane Supplements (2026)

Sulforaphane is a powerful plant compound derived primarily from broccoli sprouts and other cruciferous vegetables. It activates the Nrf2 pathway, triggering the body’s production of its own antioxidants and detoxification enzymes. Research has linked sulforaphane to cellular health, liver detoxification, anti-inflammatory activity, brain protection, and even cancer cell inhibition. Because fresh broccoli sprouts contain up to 100 times more glucoraphanin (sulforaphane’s precursor) than mature broccoli, concentrated supplements offer the most practical way to achieve therapeutic doses.

Quick Comparison

Product	Key Ingredient	Form	Best For	Rating
SMNutrition Activated Sulforaphane 50mg	Sulforaphane 50mg + Myrosinase	Microbeadlets	Best Overall	9.5/10
Double Wood Sulforaphane 20mg	Stabilized Sulforaphane 20mg	Capsules	Best Value	9.3/10
Swanson Sulforaphane from Broccoli Sprouts	Broccoli Sprout Extract 400mcg	Veggie Capsules	Best Budget Pick	9.0/10
Nextdia Liposomal Sulforaphane Gummies 150mg	Liposomal Sulforaphane 150mg	Gummies	Best Gummies	8.9/10
Liposomal Sulforaphane Gummies for Kids & Adults	Broccoli Sprout Sulforaphane	Gummies	Best for Families	8.8/10
Piping Rock Sulforaphane 400mcg	Broccoli Seed Extract 400mcg	Capsules	Best Starter Dose	8.7/10
Zooawa Mushroom + Ergothioneine Complex	Broccoli Extract + Ergothioneine	Capsules	Best Multi-Compound	8.6/10

1. SMNutrition Activated Sulforaphane 50mg – Best Overall

SMNutrition’s Activated Sulforaphane delivers a verified 50mg dose per serving using advanced microbeadlet technology and third-party potency testing – one of the few brands that can prove its sulforaphane content.

Each two-capsule serving provides 50mg of activated sulforaphane complex using BroccoRaphanin broccoli seed extract combined with BroccoPhane for maximum glucoraphanin content. The formula includes the enzyme myrosinase, which is critical for converting glucoraphanin into active sulforaphane in the body. The delayed-release microbeadlet technology protects the formula through the digestive tract, improving both absorption and stomach tolerance. What truly sets this product apart is that it undergoes third-party testing specifically to verify its active sulforaphane potency – a rarity in a category where many brands only test for total broccoli extract weight. The product is certified gluten-free, non-GMO, and allergen-free.

• Pros:
• Third-party verified for actual sulforaphane potency (50mg)
• Includes myrosinase enzyme for optimal conversion
• Delayed-release microbeadlets improve absorption and reduce GI issues

• Cons:
• Higher price per serving than basic broccoli extract capsules
• Requires two capsules per serving

Best for: Anyone who wants verified, therapeutic-dose sulforaphane with the best delivery technology available

2. Double Wood Sulforaphane 20mg – Best Value

Double Wood provides 20mg of stabilized sulforaphane per serving derived from broccoli sprouts, offering a clinically relevant dose in an affordable 120-capsule bottle.

Each two-capsule serving delivers 20mg of pure, stabilized sulforaphane extracted from broccoli sprouts. Unlike many competitors that list their broccoli extract weight (which may contain only a tiny fraction of actual sulforaphane), Double Wood specifies the sulforaphane content directly. The 120-capsule bottle provides a full 60-day supply at the recommended dose. The product is vegan-safe and uses hypromellose veggie capsules with rice flour as the only additional ingredient. Double Wood is a US-based company known for transparent labeling and third-party testing across their supplement line. For those building a comprehensive cellular health protocol, sulforaphane pairs well with NAC supplements for enhanced detoxification support.

• Pros:
• Clear labeling of actual sulforaphane content (20mg)
• 120 capsules per bottle – excellent 60-day value
• Vegan-friendly with minimal excipients

• Cons:
• Does not include myrosinase enzyme
• Lower dose than premium options (20mg vs. 50mg)

Best for: Budget-conscious users who want a verified sulforaphane dose without paying premium prices

3. Swanson Sulforaphane from Broccoli Sprouts – Best Budget Pick

Swanson’s broccoli sprout formula provides standardized sulforaphane extract at one of the lowest price points in the category, backed by nearly five decades of supplement manufacturing expertise.

Each veggie capsule contains broccoli sprout extract standardized to 0.4% sulforaphane, delivering 400mcg of sulforaphane per capsule. While this is a lower dose compared to premium products, it provides a gentle introduction to sulforaphane supplementation that supports cellular health, GI tract function, and liver health. The small, easy-to-swallow veggie capsules make daily use convenient. Swanson has been manufacturing supplements since 1969 in GMP-certified facilities, with third-party lab verification for purity and potency. The straightforward single-capsule daily dose keeps supplementation simple.

• Pros:
• One of the most affordable sulforaphane options available
• Nearly 50 years of manufacturing experience and trust
• Simple one-capsule daily dose

• Cons:
• 400mcg dose is significantly lower than therapeutic amounts used in research
• No myrosinase enzyme included for enhanced conversion

Best for: Those seeking an introductory sulforaphane supplement at a minimal cost

4. Nextdia Liposomal Sulforaphane Gummies 150mg – Best Gummies

These liposomal gummies deliver an impressive 150mg of sulforaphane per serving enhanced with vitamins C and E, offering the highest-dose gummy option with superior bioavailability.

Each serving provides 150mg of liposomal sulforaphane derived from organic broccoli sprouts, enhanced with sunflower lecithin and phosphatidylcholine for superior absorption. The liposomal delivery system encapsulates the sulforaphane in phospholipid layers, protecting it through digestion and improving cellular uptake. Additional vitamins C and E provide complementary antioxidant support. The natural green apple flavored gummies are made in a cGMP-certified facility and are non-GMO, vegan-friendly, and free from artificial colors, flavors, and preservatives. With no added sugar, these offer a clean alternative to capsule-based supplements.

• Pros:
• Highest-dose gummy option at 150mg liposomal sulforaphane
• Liposomal delivery for enhanced bioavailability
• Includes vitamins C and E for additional antioxidant support

• Cons:
• Newer brand with less long-term market presence
• Gummy form may not appeal to all users

Best for: Those who prefer gummies over capsules and want a high-dose sulforaphane option with enhanced absorption

5. Liposomal Sulforaphane Gummies for Kids & Adults – Best for Families

A family-friendly sulforaphane gummy designed for both children ages 4+ and adults, making it easy to introduce the benefits of broccoli sprout extract to picky eaters.

This liposomal sulforaphane gummy formula is specifically designed for the whole family, with appropriate dosing for children ages four and older as well as adults. The broccoli sprout extract provides sulforaphane in a liposomal form for improved absorption, delivered through tasty gummies that even the pickiest eaters enjoy. The formula targets immune support for children and broader cellular health and anti-inflammatory benefits for adults. It is manufactured in a cGMP-certified facility with clean ingredient standards. Those looking to build a comprehensive anti-aging supplement protocol will find sulforaphane an excellent foundation for cellular defense.

• Pros:
• Suitable for both kids (4+) and adults
• Liposomal delivery for better absorption
• Great taste makes daily compliance easy

• Cons:
• Lower sulforaphane concentration than adult-specific products
• Gummy form contains additional ingredients for flavor and texture

Best for: Families with children who want a shared sulforaphane supplement in a kid-friendly format

6. Piping Rock Sulforaphane 400mcg – Best Starter Dose

Piping Rock delivers broccoli seed extract standardized to 0.1% sulforaphane at 400mcg per capsule in a cost-effective 90-capsule bottle, ideal for those easing into sulforaphane supplementation.

Each quick-release capsule provides 400mcg of sulforaphane from broccoli seed extract. While this is a conservative dose, it allows users to start low and gauge their response before moving to higher-potency products. Piping Rock verifies all products through third-party registered agencies for purity, potency, and safety. The 90-capsule bottle provides a three-month supply at one capsule per day. The non-GMO, gluten-free formula uses a clean ingredient profile. Piping Rock is known for making quality supplements accessible through competitive pricing across their extensive product line.

• Pros:
• Very affordable entry point for sulforaphane supplementation
• 90-count bottle provides a full three-month supply
• Third-party verified for quality and safety

• Cons:
• 400mcg is a low dose compared to research-backed amounts
• Standardized to only 0.1% sulforaphane

Best for: First-time sulforaphane users who want to start with a low dose at an affordable price

7. Zooawa Mushroom + Ergothioneine Complex – Best Multi-Compound

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A unique formula that combines broccoli-derived compounds with ergothioneine from fermented mushroom sources, targeting multiple pathways of cellular defense and longevity support.

This innovative supplement takes a broader approach by combining cruciferous vegetable compounds with 10mg of L-ergothioneine produced through a patented fermentation process. Ergothioneine is a rare amino acid with powerful cytoprotective properties that accumulates in tissues exposed to high oxidative stress, including the brain, liver, and eyes. The mushroom-based formula provides beta-glucans alongside the cruciferous compounds for immune modulation. This multi-pathway approach targets both Nrf2 activation (via sulforaphane precursors) and direct cellular protection (via ergothioneine). For those building a comprehensive longevity stack, this pairs well with longevity supplements like NMN and resveratrol.

• Pros:
• Multi-compound approach targeting multiple cellular defense pathways
• Includes rare ergothioneine amino acid for cellular protection
• Fermentation-based production ensures consistency

• Cons:
• Lower sulforaphane-specific content than dedicated products
• More complex formula may not suit those wanting pure sulforaphane

Best for: Longevity-focused users who want a multi-compound cellular defense supplement rather than isolated sulforaphane

How to Choose the Best Sulforaphane Supplement

The most critical factor in selecting a sulforaphane supplement is understanding the difference between “broccoli extract weight” and “actual sulforaphane content.” Many products list impressive milligram amounts of broccoli extract but contain only a tiny fraction of active sulforaphane. Look for products that specify the actual sulforaphane content per serving, ideally verified by third-party testing. Research-effective doses typically range from 10mg to 50mg of actual sulforaphane per day.

Myrosinase enzyme inclusion significantly enhances sulforaphane production in the body. Glucoraphanin (the precursor to sulforaphane) requires myrosinase to convert into active sulforaphane. Some products include this enzyme directly, while others rely on your gut bacteria for conversion, which is less efficient. Products containing both glucoraphanin and myrosinase offer the most reliable conversion.

Delivery technology matters because sulforaphane is unstable and can degrade quickly. Microbeadlet technology, liposomal encapsulation, and delayed-release capsules all help protect sulforaphane through the digestive process and improve bioavailability. Standard powder-in-capsule formats may lose significant potency during digestion.

Consider the source: broccoli sprout extracts generally contain higher glucoraphanin concentrations than broccoli seed extracts. Look for products standardized to specific sulforaphane or glucoraphanin percentages, GMP-certified manufacturing, and third-party testing. Store sulforaphane supplements in a cool, dry place away from light and heat to maintain potency.

Frequently Asked Questions

What is sulforaphane and what does it do?

Sulforaphane is a naturally occurring compound formed when glucoraphanin (found in cruciferous vegetables) interacts with the enzyme myrosinase. It is one of the most potent natural activators of the Nrf2 pathway, which triggers the body to produce its own antioxidant and detoxification enzymes. Research has demonstrated its potential in supporting cellular health, reducing inflammation, protecting brain cells, supporting liver detoxification, and promoting cardiovascular health.

How much sulforaphane should I take daily?

Most clinical studies use doses between 10mg and 50mg of actual sulforaphane per day. For general wellness and antioxidant support, 10-20mg daily is a reasonable starting point. For more targeted cellular health benefits, 30-50mg daily is used in research settings. Note that “mg of broccoli extract” is not the same as “mg of sulforaphane” – always check the label for actual sulforaphane content.

When is the best time to take sulforaphane?

Sulforaphane can be taken at any time of day, though many experts recommend taking it with a meal that includes some healthy fat (such as olive oil or avocado) to improve absorption. Taking it consistently at the same time daily helps maintain steady levels. Some users prefer morning dosing to align with the body’s natural detoxification cycles.

Are there any side effects of sulforaphane?

Sulforaphane is generally well tolerated at recommended doses. Some people may experience mild digestive effects including gas, bloating, or loose stools, particularly at higher doses or when first starting supplementation. These effects typically diminish as the body adjusts. Microbeadlet and liposomal delivery systems tend to cause fewer digestive issues than standard capsules.

Can I take sulforaphane with other supplements?

Yes, sulforaphane pairs well with other Nrf2 activators and antioxidants such as curcumin, green tea extract, and resveratrol. It also complements liver-supportive supplements like NAC and milk thistle. Sulforaphane may enhance the effects of vitamin C and vitamin E. There are no significant known drug interactions, but individuals on anticoagulant medications should consult their healthcare provider due to the vitamin K content in broccoli-derived products.

How long does it take for sulforaphane to work?

Nrf2 pathway activation can begin within hours of taking sulforaphane, but noticeable health benefits typically develop over two to four weeks of consistent use. Cellular detoxification and antioxidant enzyme production build cumulatively, so longer-term supplementation tends to produce more pronounced results. Most studies evaluating clinical outcomes use protocols of four to twelve weeks.

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