Best Vitamin D3 5000 IU Supplements (2026)
Vitamin D3 at 5000 IU (125 mcg) is the go-to dosage for adults looking to correct deficiency or maintain optimal levels, particularly during months with limited sun exposure. This high-potency dose is commonly recommended by healthcare professionals for individuals whose blood levels fall below the optimal 30–50 ng/mL range. The following supplements offer the best 5000 IU options across various forms and formulations.
Quick Comparison
| Product | Added Nutrients | Form | Best For | Rating |
|---|---|---|---|---|
| Lunakai Calcium Magnesium Zinc + D3 K2 | K2, Calcium, Mag, Zinc | Gummies | Best Overall | 9.2/10 |
| Nature Made D3 5000 IU | None (pure D3) | Softgels | Best Pharmacy Brand | 9.3/10 |
| NATURELO Vitamin D 5000 IU | None (lichen-based) | Capsules | Best Vegan | 9.1/10 |
| NatureWise D3 5000 IU | Organic Olive Oil | Mini Softgels | Best Value | 9.1/10 |
| Nature’s Bounty D3 5000 IU | None (rapid release) | Softgels | Best Fast Absorption | 9.0/10 |
| Sports Research D3 5000 IU | Coconut MCT Oil | Mini Softgels | Best Premium | 9.0/10 |
| NOW Supplements D3 5000 IU | Olive Oil | Softgels | Best Large Supply | 8.9/10 |
1. Lunakai Calcium Magnesium Zinc Gummies with Vitamin D3 & K2 — Best Overall
- Daily Nutritional Support – Calcium magnesium zinc d3 supplement in a delicious gummy form to support bone health, muscle function, and immune system balance each day.
- Family-Friendly Formula – Designed for women, men, and kids, our calcium magnesium zinc gummies provide safe and effective nutritional support for the whole household.
- Naturally Flavored Gummies – Enjoy tasty peach-flavored calcium gummies with vitamin D3, made with natural flavors and absolutely no artificial colors.
- Vegan and Gluten-Free – These calcium chews with vitamin D are vegan, gelatin-free, and gluten-free, making them an easy choice for a wide range of diets.
- With Vitamin D3 & K2 MK-7 – This magnesium zinc calcium supplement includes Vitamin D3 and K2 to support proper calcium absorption and effective nutrient delivery.
Lunakai’s 5-in-1 gummy formula goes beyond standalone vitamin D by combining D3 and K2 with calcium, magnesium, and zinc — the key cofactors that maximize vitamin D’s effectiveness in the body.
This comprehensive approach addresses the common mistake of supplementing D3 in isolation. Vitamin D enhances calcium absorption, K2 directs calcium to bones, magnesium is required for D3 activation, and zinc supports immune function. By combining all five nutrients, Lunakai eliminates the need for multiple separate supplements. Manufactured in the USA in a GMP-certified facility with quality ingredients.
- Pros:
- 5-in-1 formula with all key D3 cofactors (K2, calcium, magnesium, zinc)
- Gummy format for easy daily use
- USA manufactured with GMP certification
- Cons:
- Multi-nutrient formula limits individual nutrient doses
- Contains sugar for gummy flavoring
Best for: Those who want comprehensive vitamin D support with all essential cofactors in one supplement
2. Nature Made Vitamin D3 5000 IU — Best Pharmacy Brand
- Immune, muscle, teeth and bone health support supplement: contains one 180 count bottle of Nature Made Extra Strength Vitamin D3 5000 IU (125 mcg) Softgels for a 180-day supply
- Nature Made Vitamin D 5000 IU softgels help improve calcium absorption, support bone health, teeth health, muscle health, and provide immune support
- This high dose Vitamin D 3 product is for those with higher Vitamin D needs and/or deficiency, as determined by a healthcare professional (1)
- Adults, take one Vitamin D3 Nature Made softgel daily with water and a meal
- Sourced from high-quality ingredients, this Nature Made Vit D3 supplement is gluten free and has no color added and no artificial flavors
Nature Made’s USP-Verified 5000 IU vitamin D3 softgels set the standard for pharmacy-quality supplementation, backed by independent testing that verifies purity, potency, and dissolution.
Each softgel delivers exactly 125 mcg (5000 IU) of vitamin D3 in a clean formulation with no color added and no artificial flavors. The USP verification means this product has been independently tested and confirmed to contain what the label claims, dissolve properly, and meet strict purity standards — something most supplements do not undergo. The 180-count bottle provides a 6-month supply.
- Pros:
- USP Verified — the gold standard in supplement quality assurance
- Clean formula with no artificial colors or flavors
- 180-count bottle for a full 6-month supply
- Cons:
- Contains soybean oil as a carrier
- Gelatin softgels not suitable for vegans
Best for: Anyone seeking the most rigorously tested, pharmacy-grade vitamin D3 5000 IU available
3. NATURELO Vitamin D 5000 IU Plant-Based — Best Vegan
- PLANT-BASED VITAMIN D3: Most vitamin D3 supplements are made from lanolin secreted from sheep skin. Our Vegan Vitamin D3 is sustainably sourced from wild-harvested lichen with no animal byproducts of any kind.
- HIGH POTENCY: 5000 IU of naturally bioactive Vitamin D3 can help restore blood levels in those who are deficient. Studies show that nearly half the U.S. population may be deficient in Vitamin D.*
- ESSENTIAL IMMUNE SUPPORT: Vitamin D is crucial for maintaining a healthy immune system.* Vitamin D levels may be especially low in winter or when you are stuck indoors.
- SUPPORTS BONE HEALTH: Vitamin D is necessary for your body to absorb calcium for strong bones and teeth. Risk of bone loss increases with age, particularly for women, and is also a risk during pregnancy.*
- CLEAN LABEL: Made in a GMP compliant facility. Non GMO, vegetarian, vegan, and gluten free. Does NOT contain soy, dairy, yeast, eggs, nuts, caffeine, preservatives, or coloring.
NATURELO’s plant-based 5000 IU vitamin D3 is sourced from lichen rather than sheep lanolin, making it one of the only genuinely vegan high-dose D3 options on the market.
Most vitamin D3 supplements derive cholecalciferol from lanolin (sheep’s wool grease), which excludes vegans. NATURELO uses lichen — a symbiotic organism of algae and fungi — that naturally produces D3. The formula comes in vegetable capsules with no synthetic fillers, preservatives, or additives. Third-party tested and manufactured in a GMP facility.
- Pros:
- Truly vegan D3 from lichen — not lanolin
- No synthetic fillers, binders, or additives
- Vegetable capsule suitable for vegans and vegetarians
- Cons:
- Premium price for plant-based sourcing
- No added K2 or fat carrier in the formula
Best for: Vegans and vegetarians needing a high-dose D3 supplement from a plant-based source
4. NatureWise Vitamin D3 5000 IU — Best Value
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NatureWise delivers 360 mini softgels — a full year’s supply — of 5000 IU vitamin D3 in organic extra virgin olive oil, making it the best per-serving value in the high-dose D3 category.
The organic olive oil base serves as a natural fat carrier that enhances absorption of this fat-soluble vitamin. Each mini softgel is noticeably smaller than standard capsules, making them easy to swallow. The formula is non-GMO, gluten-free, and third-party tested. NatureWise has built a strong reputation as one of Amazon’s best-selling vitamin D brands, with hundreds of thousands of positive reviews.
- Pros:
- 360 mini softgels — full year supply at exceptional value
- Organic olive oil enhances absorption
- Tiny softgels are among the easiest to swallow
- Cons:
- Gelatin-based — not suitable for vegans
- No K2 included
Best for: Value shoppers who want to buy a full year of high-dose D3 at the lowest per-serving cost
5. Nature’s Bounty Vitamin D3 5000 IU — Best Fast Absorption
- IMMUNE SUPPORT (1): Nature Bounty's Vitamin D 5000 IU provides immune support; with each rapid-release softgel aiding in the regulation of T and B-lymphocytes (1)
- SUPPORTS STRONG BONES (1): This potent Vitamin D3 formula helps with calcium absorption, and supports strong, healthy bones in adults (1)
- YOUR DAILY SUNSHINE VITAMIN: Nature's Bounty Vitamin D3 replicate the form produced by sunlight, aiding in the maintenance of optimal Vitamin D levels (1)
- NON-GMO & GLUTEN-FREE: Our Vitamin D3 5000 iu softgels are created with a non-GMO, gluten-free formula, without sugar, artificial colors, or sweeteners
- EXCEPTIONAL QUALITY: Trust Nature's Bounty's commitment to quality and value; Utilizing the latest nutritional science, we offer premium vitamins and supplements
Nature’s Bounty uses rapid-release softgel technology to deliver 5000 IU of vitamin D3 faster than standard softgels, with a non-GMO, gluten-free, sugar-free formula.
The rapid-release softgel design breaks down quickly in the digestive system for faster nutrient availability. Each softgel provides 125 mcg (5000 IU) of D3 to support immune health, calcium absorption, and bone strength. Nature’s Bounty has over 50 years in the supplement industry and maintains rigorous quality testing standards. The formula contains no sugar, artificial colors, or sweeteners.
- Pros:
- Rapid-release softgel technology for faster absorption
- No sugar, artificial colors, or sweeteners
- Trusted brand with over 50 years in the supplement industry
- Cons:
- Not USP verified (unlike Nature Made)
- Gelatin softgels not suitable for vegans
Best for: Those who want fast-absorbing vitamin D3 from a well-established, trusted brand
6. Sports Research Vitamin D3 5000 IU with Coconut MCT Oil — Best Premium
- SHINE BRIGHT: Vitamin D3 helps the body absorb calcium and phosphorus - essential minerals for maintaining strong bones and teeth. It's also known as the 'sunshine vitamin', with adequate levels providing immune system support and muscular wellness so you can shine at your brightest.*
- ONE-A-DAY FORMULA: Just one easy-to-swallow liquid softgel daily provides 125 mcg (5,000 iu) of high potency Vitamin D3 as cholecalciferol - the body's preferred form of Vitamin D.*
- WITH COCONUT MCT OIL: Vitamin D-3 delivers the best benefits when taken with food or another source of fat, which is why we add medium chain triglycerides (MCT), the best fats from coconut oil, to our softgels to help ensure that you get the most from this essential micronutrient.*
- PREMIUM QUALITY: We hold all of our supplements to a higher standard. Sports Research Vitamin D3 softgels are IGEN Non-GMO tested, and free of unwanted fillers, gluten, and seed oils such as soybean & safflower oil. Each batch is third-party tested for quality and manufactured in the USA in a cGMP-compliant facility.
- THE SPORTS RESEARCH DIFFERENCE: Founded in 1980, Sports Research is a family-owned business born from a passion for fitness and wellness. Our goal is to embrace the sport of life through research-backed products created for every body—inside and out.
Sports Research suspends 5000 IU of vitamin D3 in coconut MCT oil for superior absorption, packaged in mini softgels with non-GMO verification and a seed-oil-free formula.
MCT (medium-chain triglyceride) oil from coconut is one of the most effective fat carriers for fat-soluble vitamins, potentially offering better absorption than soybean or olive oil. Each mini softgel is easy to swallow and provides a clean, single-ingredient dose. Sports Research is Non-GMO Project Verified and manufactured in a GMP facility. The 360-count bottle provides a full year’s supply.
- Pros:
- Coconut MCT oil carrier for optimal fat-soluble vitamin absorption
- 360-count bottle — full year supply
- Non-GMO verified, seed-oil-free, and gluten-free
- Cons:
- Premium pricing compared to basic D3 softgels
- Gelatin-based (vegan version available separately with K2)
Best for: Health-conscious individuals who want the best possible absorption from their D3 supplement
7. NOW Supplements Vitamin D3 5000 IU — Best Large Supply
- HIGH POTENCY/SUNSHINE VITAMIN: Highly-absorbable liquid softgel form of vitamin D3
- VITAMIN D: Supports healthy immune system function and is essential for achieving and maintaining optimal bone mineral density*
- CERTIFICATIONS/CLASSIFICATIONS: Corn Free, Dairy Free, Egg Free, Halal, Kosher Contains Gelatin, Made without Gluten, Non-GMO, Soy Free
- GMP Quality Assured: A-rated, third-party certification means that every aspect of the NOW manufacturing process has been examined. Our in-house laboratories are ISO/IEC accredited for laboratory testing including for stability, potency and product formulation.
- Packaged in the USA by a family owned and operated company since 1968
NOW Foods delivers 240 high-potency 5000 IU vitamin D3 softgels in extra virgin olive oil at one of the most competitive prices in the category, backed by GMP certification and decades of supplement expertise.
Each softgel contains 125 mcg (5000 IU) of vitamin D3 as cholecalciferol from lanolin, suspended in extra virgin olive oil and safflower oil. NOW Foods has been a trusted name in the natural products industry since 1968, maintaining strict GMP standards and extensive quality testing. The formula is free from yeast, wheat, gluten, soy, corn, milk, egg, fish, and shellfish ingredients.
- Pros:
- 240-count bottle at a competitive price point
- Olive oil base for enhanced absorption
- Free from major allergens — extensive allergen testing
- Cons:
- Contains bovine gelatin — not suitable for vegans or vegetarians
- No K2 included
Best for: Those seeking a well-priced, large-supply vitamin D3 from a trusted legacy supplement brand
8. Natures Craft Vitamin D3 with K2 MK7 — Best D3+K2 Combo
- Immune booster for adults - Vitamin D3 2000 IU and Vitamin K2 are the top immunity vitamins for that much needed immune boost to keep your immune system fighting off invaders for optimal immune health
- Vitamin K2 with D3 supplement - Try our halal vitamin D3 K2 2000 IU and feels the difference in how you look and feel thanks to these Hair vitamins for faster hair growth and Natural Energy supplement
- Heart health supplement - Vit D3 supplements support a healthy heart but the D3 K2 vitamin combination adds more by redirecting calcium in the body which can remineralize teeth while helping your heart
- Joint supplements for men and women - Our K2 D3 vitamin supplement redirects calcium away from the heart which promotes stronger teeth and joint health plus hair growth vitamins keep locks healthy too
- Mood lift supplement - Vit D3 2000 IU works wonders as an immune supplement that also provides mood support so our halal vitamin D3 K2 2000 can help make you feel better and more stable
Natures Craft combines vitamin D3 with K2 in the highly bioavailable MK-7 form, providing the synergistic bone and cardiovascular support that D3 alone cannot deliver.
The D3+K2 combination is increasingly recommended by health professionals because D3 enhances calcium absorption while K2 (as MK-7) ensures calcium is deposited in bones rather than arteries. This affordable combination tablet makes it easy to get both nutrients in a single daily dose. The formula supports immune health, bone density, and cardiovascular function.
- Pros:
- D3+K2 combination for superior bone and cardiovascular support
- K2 as MK-7 — the most bioactive and long-lasting form
- Affordable price point for a combination formula
- Cons:
- D3 dose is 2000 IU — lower than the 5000 IU focus of this article
- Tablet format may not appeal to all users
Best for: Those seeking an affordable D3+K2 combination for daily bone and immune support
How to Choose the Best Vitamin D3 5000 IU Supplement
Verify that the supplement contains D3 (cholecalciferol) rather than D2 (ergocalciferol). D3 is 87% more effective at raising blood levels and maintaining them over time. Most quality supplements specify “D3” or “cholecalciferol” on the label.
Consider the carrier oil. Since vitamin D is fat-soluble, supplements suspended in oil (olive oil, MCT oil, coconut oil) generally absorb better than dry tablets or capsules. If you choose a dry format, take it with a meal containing fat.
Look for third-party testing and quality certifications. USP Verification (United States Pharmacopeia) is the gold standard, confirming purity, potency, and dissolution. NSF International and ConsumerLab are also reputable third-party verifiers. GMP (Good Manufacturing Practice) certification should be considered the baseline expectation.
Decide whether you want a standalone D3 or a D3+K2 combination. Adding K2 (especially as MK-7) improves calcium metabolism and provides additional cardiovascular protection. If you take D3 alone, consider adding a separate K2 supplement, particularly at the 5000 IU dose level where calcium absorption is significantly enhanced.
Frequently Asked Questions
Who should take 5000 IU of vitamin D3?
The 5000 IU dose is typically recommended for adults with diagnosed vitamin D deficiency or insufficiency (blood levels below 30 ng/mL), those with limited sun exposure, individuals with darker skin pigmentation, adults over 65, and people with conditions affecting fat absorption. Always confirm with a blood test and healthcare provider guidance.
Is 5000 IU of vitamin D3 safe to take daily?
For most adults, 5000 IU daily is considered safe and well within the tolerable upper limit of 4000–10,000 IU established by various health organizations. However, prolonged supplementation at this level should be monitored with periodic blood tests to ensure levels remain in the optimal 30–50 ng/mL range.
When is the best time to take vitamin D3 5000 IU?
Take vitamin D3 with your largest meal of the day, ideally one that contains healthy fats (avocado, nuts, olive oil, eggs). Since D3 is fat-soluble, absorption improves dramatically when consumed with dietary fat. Some studies suggest morning or midday intake may be slightly preferable to evening dosing.
How long does it take for 5000 IU to correct a deficiency?
At 5000 IU daily, most adults see meaningful increases in blood levels within 4–6 weeks, with levels typically stabilizing within 8–12 weeks. Starting levels, body weight, and individual absorption rates all influence the timeline. Severely deficient individuals may need a brief loading dose as prescribed by their provider.
Can I take vitamin D3 5000 IU with other supplements?
Vitamin D3 pairs well with most supplements and is commonly taken alongside K2, calcium, magnesium, and omega-3 fatty acids. Avoid taking D3 at the same time as iron or high-dose calcium, as these can compete for absorption. Spacing supplements 2–3 hours apart can optimize uptake of each.
What are the signs of vitamin D deficiency?
Common symptoms include fatigue, frequent illness or infection, bone and back pain, muscle weakness, mood changes (particularly seasonal depression), slow wound healing, and hair loss. However, many people with deficiency are asymptomatic, which is why blood testing is the most reliable diagnostic method.
