Best Vitamin K2 MK-7 Supplements (2026)

Vitamin K2 in the MK-7 form has become one of the most sought-after supplements for bone and cardiovascular health. MK-7, derived primarily from natto (fermented soybeans), has a significantly longer half-life than other K2 forms, allowing it to remain active in the body for up to 72 hours. It works by directing calcium into bones and teeth while keeping it out of arteries and soft tissues. Pairing K2 MK-7 with vitamin D3 has become standard practice for optimizing calcium metabolism.

Quick Comparison

Product	Key Ingredient	Form	Best For	Rating
VITBOOST Vitamin D3 K2 Complex	D3 5000 IU + K2 MK-7 200mcg	Capsules	Best Overall	9.5/10
Vitamin K2 MK-7 Gummies 100mcg	K2 MK-7 100mcg	Gummies	Best Gummies	9.3/10
DaVinci Labs ADK 10	Vitamins A + D3 + K2 MK-7	Capsules	Best ADK Complex	9.2/10
Vitamatic D3 K2 10000 IU	D3 10000 IU + K2 MK-7 200mcg	Softgels	Best High-Dose	9.1/10
Dr. Mercola Vitamin D3 K2 3000 IU	D3 3000 IU + K2 MK-7	Capsules	Best Moderate Dose	9.0/10
D3K2 Enhanced with Calcium & BioPerine	D3 5000 IU + K2 MK-7 + Calcium	Capsules	Best All-in-One Bone Formula	8.9/10
Innovix Labs Full Spectrum Vitamin K2	K2 MK-7 + MK-4 600mcg	Capsules	Best Full Spectrum K2	8.8/10

1. VITBOOST Vitamin D3 K2 Complex – Best Overall

A perfectly dosed D3 + K2 MK-7 formula that delivers the most popular combination for calcium metabolism, bone density, and cardiovascular protection.

VITBOOST combines 5000 IU of vitamin D3 with 200mcg of vitamin K2 as MK-7 in easy-to-swallow capsules. This D3-to-K2 ratio is widely considered optimal by nutritional researchers — the D3 enhances calcium absorption while the K2 ensures that calcium is deposited in bones and teeth rather than accumulating in arteries and soft tissues. The formula is non-GMO, gluten-free, and manufactured in a GMP-certified facility. For anyone taking vitamin D3, adding K2 MK-7 is essential to avoid the potential cardiovascular risks of elevated calcium without proper directing. This is the combination most frequently recommended by integrative health practitioners.

• Pros:
• Optimal D3/K2 ratio recommended by most practitioners
• 200mcg MK-7 provides a clinically relevant K2 dose
• Convenient single-capsule daily serving

• Cons:
• 5000 IU D3 may need adjustment based on blood levels
• No added calcium or magnesium for complete bone stack

Best for: Anyone taking vitamin D3 who wants the essential K2 MK-7 companion at a clinically effective dose for bone and heart health.

2. Vitamin K2 MK-7 Gummies 100mcg – Best Gummies

An extra-strength K2 MK-7 gummy that makes daily supplementation enjoyable for those who dislike swallowing capsules.

These K2 MK-7 gummies deliver 100mcg per serving in a pleasant-tasting chewable format designed for bone and cardiovascular health support. Gummies are the fastest-growing supplement format and offer a real compliance advantage — people who skip capsule-based supplements often stick with gummies. The K2 as MK-7 form ensures the longest-lasting activity in the body, with a half-life significantly longer than the MK-4 form. For those already taking a standalone D3 supplement, adding these K2 gummies completes the calcium metabolism picture without switching products. Pairing with a quality calcium and D3 supplement creates a comprehensive bone health regimen.

• Pros:
• Easy to take for those who struggle with pills or capsules
• Standalone K2 allows flexible dosing with separate D3
• Pleasant taste encourages daily compliance

• Cons:
• Contains added sugars and flavoring typical of gummies
• Lower dose than capsule-based K2 supplements

Best for: People who prefer gummies over capsules and want to add K2 MK-7 to their existing supplement regimen.

3. DaVinci Labs ADK 10 – Best ADK Complex

A physician-formulated ADK complex combining vitamins A, D3, and K2 for synergistic bone, immune, and cardiovascular support from a trusted clinical brand.

DaVinci Labs ADK 10 delivers vitamin A (as retinyl palmitate), vitamin D3 (10,000 IU), and vitamin K2 (as MK-7) in a single capsule. This “ADK” combination is based on the synergistic relationship between these three fat-soluble vitamins — vitamin A supports immune function and cell growth, D3 drives calcium absorption, and K2 directs calcium to bones. DaVinci Labs is a healthcare practitioner brand with rigorous quality standards, making this a favorite among functional medicine doctors. The higher D3 dose makes this suitable for those with confirmed deficiency under practitioner guidance.

• Pros:
• Three synergistic fat-soluble vitamins in one capsule
• Healthcare practitioner-grade quality and formulation
• Trusted brand in the integrative and functional medicine space

• Cons:
• 10,000 IU D3 is high and requires monitoring of blood levels
• Higher price than consumer-grade D3/K2 combos

Best for: Those working with a healthcare practitioner who want a comprehensive fat-soluble vitamin complex with clinical-grade quality.

4. Vitamatic D3 K2 10000 IU – Best High-Dose

A high-potency D3 and K2 softgel for those with significant vitamin D deficiency who need aggressive repletion alongside K2 protection.

Vitamatic combines 10,000 IU of vitamin D3 with 200mcg of vitamin K2 MK-7 in a small softgel format. This high-dose option is designed for individuals with clinically low vitamin D levels who need to rapidly restore adequate status. The K2 MK-7 component is particularly important at this D3 dosage — as D3 significantly increases calcium absorption, K2 ensures that calcium doesn’t accumulate in arteries. The softgel uses a fat base for enhanced absorption of these fat-soluble vitamins. Non-GMO, gluten-free, and free of common allergens.

• Pros:
• High-dose D3 for rapid deficiency correction
• K2 MK-7 at 200mcg provides essential calcium trafficking protection
• Small softgel format for easy daily dosing

• Cons:
• 10,000 IU D3 should only be used with blood level monitoring
• Not appropriate for long-term maintenance in most people

Best for: Individuals with confirmed severe vitamin D deficiency who need high-dose repletion with K2 cardiovascular protection.

5. Dr. Mercola Vitamin D3 K2 3000 IU – Best Moderate Dose

A moderate-strength D3 and K2 formula ideal for daily maintenance supplementation without the risks of high-dose vitamin D.

Dr. Mercola’s formula provides 3000 IU of vitamin D3 with vitamin K2 as MK-7 from natto in a convenient capsule. This moderate dose is well-suited for daily maintenance once adequate vitamin D levels have been achieved, or for those who get some sun exposure and dietary vitamin D but want to ensure sufficiency. The natto-derived MK-7 source is the most researched form of K2 with the longest biological half-life. Dr. Mercola is a well-known figure in the natural health space, and his supplement line emphasizes quality sourcing and evidence-based formulations.

• Pros:
• Moderate D3 dose appropriate for long-term daily maintenance
• Natto-derived MK-7 — the most studied K2 source
• Suitable for those with partial sun exposure who need moderate supplementation

• Cons:
• 3000 IU may be insufficient for those with significant deficiency
• Does not specify exact MK-7 dose as prominently as competitors

Best for: Those seeking a moderate, everyday D3 + K2 supplement for maintenance rather than deficiency correction.

6. D3K2 Enhanced with Calcium & BioPerine – Best All-in-One Bone Formula

A comprehensive bone health formula combining D3, K2 MK-7, calcium, and BioPerine absorption enhancer in a single supplement.

This all-in-one formula delivers 5000 IU of vitamin D3, 100mcg of vitamin K2 MK-7, calcium, and BioPerine (black pepper extract) for enhanced absorption. The addition of calcium directly provides the mineral that D3 and K2 work together to metabolize, while BioPerine increases the bioavailability of all ingredients. This eliminates the need to purchase separate calcium, D3, and K2 supplements — an advantage for those who want to simplify their bone health stack. For comprehensive bone support in older adults, pairing with a dedicated bone health supplement can provide additional trace minerals.

• Pros:
• All-in-one formula replaces 3 separate supplements
• BioPerine enhances absorption of all active ingredients
• Balanced D3/K2/calcium ratio for bone mineralization

• Cons:
• Calcium dose may be modest compared to dedicated calcium supplements
• Multiple ingredients mean less flexibility in adjusting individual doses

Best for: Those who want a simplified bone health stack with D3, K2, and calcium in a single daily supplement.

7. Innovix Labs Full Spectrum Vitamin K2 – Best Full Spectrum K2

The only K2 supplement on this list that provides BOTH MK-7 and MK-4 forms for comprehensive vitamin K2 activity across all body tissues.

Innovix Labs delivers a full-spectrum vitamin K2 formula with both MK-7 (from natto) and MK-4 forms, totaling 600mcg per capsule. While MK-7 has a long half-life and is excellent for cardiovascular and bone health, MK-4 is the form that the body naturally produces and uses in the brain, kidneys, and reproductive organs. By combining both forms, this supplement covers the complete range of K2 activity throughout the body. This is an ideal choice for those who want pure K2 without D3 — allowing full control over D3 dosing with a separate supplement. Each bottle provides a generous supply at a competitive per-capsule cost.

• Pros:
• Both MK-7 and MK-4 forms for full-body K2 coverage
• High total K2 dose at 600mcg per capsule
• Standalone K2 allows pairing with any D3 dose

• Cons:
• Does not include D3 — requires separate supplementation
• Higher K2 dose than most people need unless directed by a practitioner

Best for: Those who want the most comprehensive K2 supplement covering all tissue-specific forms, with the flexibility to control D3 dosing separately.

8. Sports Research Vitamin D3 + K2 with Coconut Oil – Best for Absorption

A vegan-certified D3 and K2 MK-7 formula in a coconut oil base that maximizes fat-soluble vitamin absorption.

Sports Research combines 5000 IU of vegan vitamin D3 with 100mcg of vitamin K2 MK-7 in a coconut oil base for optimal absorption. The coconut oil carrier ensures these fat-soluble vitamins are delivered with the dietary fat needed for uptake — a common issue with dry-capsule D3 supplements that are taken without food. The formula is vegan-certified, non-GMO, soy-free, and manufactured under strict GMP standards. Sports Research is consistently one of the top-rated supplement brands on Amazon, known for transparent labeling and rigorous third-party testing. For those exploring broader vitamin D3 options, liquid forms offer alternative delivery methods.

• Pros:
• Coconut oil base ensures fat-soluble vitamin absorption even without food
• Vegan-certified D3 — rare in the market
• Excellent brand reputation with consistent third-party testing

• Cons:
• 100mcg K2 is lower than the 200mcg found in some competitors
• Contains coconut — not suitable for those with coconut allergies

Best for: Vegans and anyone who wants a well-absorbed D3 + K2 formula backed by one of Amazon’s most trusted supplement brands.

How to Choose the Best Vitamin K2 MK-7 Supplement

The MK-7 form of vitamin K2 is preferred over MK-4 for most supplementation purposes because of its significantly longer half-life — MK-7 remains active in the body for approximately 72 hours compared to just a few hours for MK-4. This means daily dosing with MK-7 maintains more consistent blood levels. Look for supplements that specify “MK-7” or “menaquinone-7” rather than just “vitamin K2,” as the form makes a significant difference in effectiveness.

Most research supports doses between 100-200mcg of K2 MK-7 daily for bone and cardiovascular health. Higher doses up to 600mcg may be appropriate under practitioner guidance. If you’re taking vitamin D3, pairing it with K2 is considered essential by many nutrition experts to ensure proper calcium metabolism and prevent arterial calcification.

For fat-soluble vitamins like K2, absorption matters. Choose supplements that include a fat carrier (coconut oil, MCT oil, or olive oil) or take them with a fat-containing meal. Softgels generally absorb better than dry capsules for fat-soluble nutrients. Third-party testing for purity and potency adds an extra layer of quality assurance.

Consider whether you want a standalone K2 supplement (for maximum dosing flexibility) or a combination D3+K2 formula (for convenience). Both approaches are effective — it depends on whether you already take D3 separately and want to add K2, or prefer an all-in-one solution.

Frequently Asked Questions

What is vitamin K2 MK-7 and what does it do?

Vitamin K2 MK-7 (menaquinone-7) is a form of vitamin K2 primarily derived from natto, a traditional Japanese fermented soybean food. Its primary role is activating proteins that direct calcium into bones and teeth while preventing calcium from depositing in arteries and soft tissues. This makes it essential for both bone density and cardiovascular health. MK-7 has the longest half-life of all K2 forms, providing sustained activity throughout the body.

How much vitamin K2 MK-7 should I take daily?

Research supports 100-200mcg of K2 MK-7 daily for general bone and cardiovascular health. Most combination D3+K2 supplements provide 100-200mcg. Higher doses may be recommended by healthcare practitioners for specific conditions like osteoporosis or arterial calcification. There is no established upper limit for K2, and it is generally considered very safe even at higher doses.

Should I take K2 MK-7 with vitamin D3?

Yes. Vitamin D3 increases calcium absorption from the gut, but without adequate K2, that calcium may deposit in arteries rather than bones. K2 MK-7 activates the proteins (osteocalcin and matrix GLA protein) that direct calcium to its proper destinations. Most integrative health practitioners now recommend always pairing D3 with K2 for optimal calcium metabolism.

What is the difference between K2 MK-7 and K2 MK-4?

MK-7 is derived from bacterial fermentation (primarily natto) and has a half-life of about 72 hours, maintaining consistent blood levels with daily dosing. MK-4 is the form the body naturally synthesizes and has a very short half-life of just a few hours, requiring multiple daily doses for sustained effects. MK-7 is more practical for supplementation, while MK-4 has unique tissue-specific benefits in the brain and reproductive organs.

Can I take vitamin K2 if I’m on blood thinners?

Vitamin K2 can interfere with warfarin and other vitamin K-dependent blood thinners by counteracting their mechanism of action. If you take warfarin or similar anticoagulants, do not take K2 supplements without first consulting your prescribing physician. Newer anticoagulants (DOACs) like apixaban and rivarelbxaban work through different mechanisms and may not interact with K2, but medical consultation is still essential.

When is the best time to take vitamin K2 MK-7?

Take K2 MK-7 with a meal that contains dietary fat for optimal absorption. Since K2 is fat-soluble, it requires a fat carrier for proper uptake. If your supplement is in a softgel with an oil base (coconut oil or olive oil), absorption is less dependent on meal timing. Many people take their D3+K2 supplement with breakfast or dinner as part of their daily routine.

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